Evidence map›Paper›PMID 27553837›Full record

Observational studyHPB : the official journal of the International Hepato Pancreato Biliary Association2016

Long-term outcomes of resection in patients with symptomatic benign liver tumours.

Belle V van Rosmalen, Matthanja Bieze, Marc G H Besselink, Pieter Tanis, Joanne Verheij, Saffire S K S Phoa, Olivier Busch, Thomas M van Gulik

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Current Approaches in the Management of Hepatic Adenomas.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Review
  7. Review
  8. Indications for liver surgery in benign tumours.European surgery : ACA : Acta chirurgica Austriaca · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Belle V van RosmalenDepartment of Surgery, Academic Medical Centre, Amsterdam, The Netherlands. Electronic address: b.v.vanrosmalen@amc.uva.nl.
Matthanja BiezeDepartment of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
Marc G H BesselinkDepartment of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
Pieter TanisDepartment of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
Joanne VerheijDepartment of Pathology, Academic Medical Centre, Amsterdam, The Netherlands.
Saffire S K S PhoaDepartment of Radiology, Academic Medical Centre, Amsterdam, The Netherlands.
Olivier BuschDepartment of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
Thomas M van GulikDepartment of Surgery, Academic Medical Centre, Amsterdam, The Netherlands. Electronic address: t.m.vangulik@amc.nl.
Amsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign liver tumours (e.g., hepatocellular adenoma (HCA), focal nodular hyperplasia (FNH), and haemangioma) are occasionally resected for alleged symptoms, although data on long-term outcomes is lacking. The aim of this cross-sectional study was to assess long-term outcomes of surgical intervention.

methodsForty patients with benign tumours (HCA 20, FNH 12, giant haemangioma 4, cysts 4) were included. Patients filled in Validated McGill Pain Questionnaires, preoperatively and after a median of 54 months after resection. Outcomes were evaluated using paired sample t-test and (M) ANOVA.

resultsRelief of symptoms sustained in 30/40 patients, within a follow-up of 54 (24-148) months after resection. VAS scores were reduced from 5.5 preoperatively to 1.6 postoperatively (p < 0.001). Patients with left-sided tumours had higher postoperative Pain Rating Index (PRI), compared to patients with right-sided tumours: 15.3 vs. 5.8 (p = 0.018). If patients could reconsider undergoing surgery, 34/38 would again choose resection. Discomfort at the operative scar was the most common complaint: 8/40 patients, all after open surgery, of whom 3/40 had an incisional hernia. 7/40 patients had a laparoscopic resection.

conclusionResection relieved symptoms in 30/40 patients. The operative scar was a frequent source for remaining postoperative complaints, suggesting an advantage for a laparoscopic approach when feasible.

Indexed as

HepatectomyAdenoma, Liver CellAdultAgedCicatrixCross-Sectional StudiesFemaleFocal Nodular HyperplasiaHemangiomaHumansIncisional HerniaLiver NeoplasmsMaleMiddle AgedPain MeasurementPatient Satisfaction

Identifiers

PMID27553837
PMCPMC5094485
OpenAlexW2344332345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.