Evidence map›Paper›PMID 27553803›Full record

ArticleSurgical endoscopy2017

Efficacy of magnetic sphincter augmentation in patients with large hiatal hernias.

Kais A Rona, Jessica Reynolds, Katrin Schwameis, Joerg Zehetner, Kamran Samakar, Paul Oh, David Vong, Kulmeet Sandhu, Namir Katkhouda, Nikolai Bildzukewicz and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Magnetic Sphincter Augmentation After Gastric Surgery.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Pooled it
  6. Trial
  7. Article
  8. Longer-term outcomes of gastroesophageal reflux disease treated with magnetic sphincter augmentation.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Article
  9. The role of magnetic sphincter augmentation in the gastroesophageal reflux disease treatment pathway: the gastroenterology perspective.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Magnetic challenge against gastroesophageal reflux.World journal of gastroenterology · 2021
    Review
  14. Evolution of a novel technology for gastroesophageal reflux disease: a safety perspective of magnetic sphincter augmentation.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. A narrative review of gastroesophageal reflux in the pediatric patient.Translational gastroenterology and hepatology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Kais A RonaKeck School of Medicine of USC, Los Angeles, CA, USA.
Jessica ReynoldsKeck School of Medicine of USC, Los Angeles, CA, USA.
Katrin SchwameisKeck School of Medicine of USC, Los Angeles, CA, USA.
Joerg ZehetnerKeck School of Medicine of USC, Los Angeles, CA, USA.
Kamran SamakarKeck School of Medicine of USC, Los Angeles, CA, USA.
Paul OhKeck School of Medicine of USC, Los Angeles, CA, USA.
David VongKeck School of Medicine of USC, Los Angeles, CA, USA.
Kulmeet SandhuKeck School of Medicine of USC, Los Angeles, CA, USA.
Namir KatkhoudaKeck School of Medicine of USC, Los Angeles, CA, USA.
Nikolai BildzukewiczKeck School of Medicine of USC, Los Angeles, CA, USA.
John C LiphamKeck School of Medicine of USC, Los Angeles, CA, USA. john.lipham@med.usc.edu.
Keck Hospital of USC · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnetic sphincter augmentation (MSA) has demonstrated long-term safety and efficacy in the treatment of patients with gastroesophageal reflux (GERD), but its efficacy in patients with large hiatal hernias has yet to be proven. The aim of our study was to assess outcomes of MSA in patients with hiatal hernias ≥3 cm.

methodsWe retrospectively reviewed all patients who underwent MSA at our institutions over a 6-year period. Information obtained consisted of patient demographics, symptoms of GERD, preoperative GERD Health-Related Quality-of-Life (HRQL) scores, perioperative details, and implantation of the MSA device. Primary endpoints included postoperative GERD-HRQL scores, proton-pump inhibitor (PPI) use, symptom change, and procedure-related complications. A large hiatal hernia was defined as a hernia measuring ≥3 cm by intraoperative measurement.

resultsA total of 192 patients were reviewed. Median follow-up was 20 months (3-75 months). Mean GERD-HRQL scores in the overall population before and after MSA were 18.9 and 5.0, respectively (p < 0.001). In the majority of patients symptoms improved or resolved (N = 177, p < 0.001). Fifty-two patients (27.0 %) had a hiatal hernia ≥3 cm (range 3-7 cm). Their mean GERD-HRQL score decreased from 20.5 to 3.6 (p < 0.001) following MSA. When compared to patients with smaller hernias, patients with large hiatal hernias had decreased postoperative PPI requirement (9.6 vs. 26.6 %, p = 0.011) and lower mean postoperative GERD-HRQL scores (3.6 vs. 5.6, p = 0.027). The percent of patients requiring postoperative intervention for dysphagia was similar (13.5 vs. 17.9 %, p = 0.522), as was the incidence of symptom resolution or improvement (98.1 vs. 91.3 %, p = 0.118).

conclusionMSA in patients with large hiatal hernias demonstrates decreased postoperative PPI requirement and mean GERD-HRQL scores compared to patients with smaller hernias. The incidence of symptom resolution or improvement and the percentage of patients requiring intervention for dysphagia are similar. Short-term outcomes of MSA are encouraging in patients with gastroesophageal reflux disease and large hiatal hernias.

Indexed as

AdolescentAdultAgedAged, 80 and overEsophageal Sphincter, LowerFemaleGastroesophageal RefluxHernia, HiatalHumansLaparoscopyMagnetic Field TherapyMaleMiddle AgedProton Pump InhibitorsQuality of LifeRetrospective StudiesProton Pump InhibitorsGERDHiatal herniaLINXMagnetic sphincter augmentationMSA

Identifiers

PMID27553803
OpenAlexW2510600238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.