ArticleScientific reports2016
PPP1, a plant-specific regulator of transcription controls Arabidopsis development and PIN expression.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Rocks in the auxin stream: Wound-induced auxin accumulation andProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Functional Coordination of the Chromatin-Remodeling Factor AtINO80 and the Histone Chaperones NRP1/2 in Inflorescence Meristem and Root Apical Meristem.Frontiers in plant science · 2019Article
- The PIN-FORMED Auxin Efflux Carriers in Plants.International journal of molecular sciences · 2018Review
- Auxin transport and conjugation caught together.Journal of experimental botany · 2017Article
Corrections and comments
- Retraction · 2021-04-08Doing the Right Thing · Error in Analyses · Error in Cell Lines/Tissues · Results Not Reproducible ·
- Retracted
Authors and funding
14 authors.
Funding
Abstract
Directional transport of auxin is essential for plant development, with PIN auxin transport proteins representing an integral part of the machinery that controls hormone distribution. However, unlike the rapidly emerging framework of molecular determinants regulating PIN protein abundance and subcellular localization, insights into mechanisms controlling PIN transcription are still limited. Here we describe PIN2 PROMOTER BINDING PROTEIN 1 (PPP1), an evolutionary conserved plant-specific DNA binding protein that acts on transcription of PIN genes. Consistent with PPP1 DNA-binding activity, PPP1 reporter proteins are nuclear localized and analysis of PPP1 null alleles and knockdown lines indicated a function as a positive regulator of PIN expression. Furthermore, we show that ppp1 pleiotropic mutant phenotypes are partially reverted by PIN overexpression, and results are presented that underline a role of PPP1-PIN promoter interaction in PIN expression control. Collectively, our findings identify an elementary, thus far unknown, plant-specific DNA-binding protein required for post-embryonic plant development, in general, and correct expression of PIN genes, in particular.
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Registered trials
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