ArticleBMC plant biology2016
Multi-environment QTL studies suggest a role for cysteine-rich protein kinase genes in quantitative resistance to blackleg disease in Brassica napus.
Article in BMC plant biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Meta-analysis of GWAS in canola blackleg (Leptosphaeria maculans) disease traits demonstrates increased power from imputed whole-genome sequence.Scientific reports · 2020Pooled it
- Experimental dissection of phenotypic variation for quantitative disease resistance in canola (Brassica napus) - Leptosphaeria maculans interactions.Pest management science · 2026Article
- Quantifying Genetic Parameters for Blackleg Resistance in Rapeseed: A Comparative Study.Plants (Basel, Switzerland) · 2024Article
- DArTseq-Based, High-Throughput Identification of Novel Molecular Markers for the Detection of Blackleg (International journal of molecular sciences · 2024Article
- Breeding and management of major resistance genes to stem canker/blackleg in Brassica crops.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- Review
- Article
- Independent breakdown events of the Brassica napus Rlm7 resistance gene including via the off-target impact of a dual-specificity avirulence interaction.Molecular plant pathology · 2022Article
- Characterization of non-specific lipid transfer protein (nsLtp) gene families in the Brassica napus pangenome reveals abundance variation.BMC plant biology · 2022Article
- Construction of a Quantitative Genomic Map, Identification and Expression Analysis of Candidate Genes for Agronomic and Disease-Related Traits inFrontiers in plant science · 2022Article
- Tandem Protein Kinases Emerge as New Regulators of Plant Immunity.Molecular plant-microbe interactions : MPMI · 2021Review
- A gene-for-gene interaction involving a 'late' effector contributes to quantitative resistance to the stem canker disease in Brassica napus.The New phytologist · 2021Article
- A wheat cysteine-rich receptor-like kinase confers broad-spectrum resistance against Septoria tritici blotch.Nature communications · 2021Article
- Dissection of Quantitative Blackleg Resistance Reveals Novel Variants of Resistance GeneFrontiers in plant science · 2021Article
- Exploring Mechanisms of Quantitative Resistance toPlants (Basel, Switzerland) · 2020Article
- Genomic Prediction and Genetic Correlation of Agronomic, Blackleg Disease, and Seed Quality Traits in Canola (Plants (Basel, Switzerland) · 2020Article
- Characterization of disease resistance genes in the Brassica napus pangenome reveals significant structural variation.Plant biotechnology journal · 2020Article
- Genetic and physical mapping of loci for resistance to blackleg disease in canola (Brassica napus L.).Scientific reports · 2020Article
- Genome-Wide Association Mapping Identifies Novel Loci for Quantitative Resistance to Blackleg Disease in Canola.Frontiers in plant science · 2020Article
- An update on the arsenal: mining resistance genes for disease management ofHorticulture research · 2020Review
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResistance to the blackleg disease of Brassica napus (canola/oilseed rape), caused by the hemibiotrophic fungal pathogen Leptosphaeria maculans, is determined by both race-specific resistance (R) genes and quantitative resistance loci (QTL), or adult-plant resistance (APR). While the introgression of R genes into breeding material is relatively simple, QTL are often detected sporadically, making them harder to capture in breeding programs. For the effective deployment of APR in crop varieties, resistance QTL need to have a reliable influence on phenotype in multiple environments and be well defined genetically to enable marker-assisted selection (MAS).
resultsDoubled-haploid populations produced from the susceptible B. napus variety Topas and APR varieties AG-Castle and AV-Sapphire were analysed for resistance to blackleg in two locations over 3 and 4 years, respectively. Three stable QTL were detected in each population, with two loci appearing to be common to both APR varieties. Physical delineation of three QTL regions was sufficient to identify candidate defense-related genes, including a cluster of cysteine-rich receptor-like kinases contained within a 49 gene QTL interval on chromosome A01. Individual L. maculans isolates were used to define the physical intervals for the race-specific R genes Rlm3 and Rlm4 and to identify QTL common to both field studies and the cotyledon resistance response.
conclusionThrough multi-environment QTL analysis we have identified and delineated four significant and stable QTL suitable for MAS of quantitative blackleg resistance in B. napus, and identified candidate genes which potentially play a role in quantitative defense responses to L. maculans.
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