ArticleLangmuir : the ACS journal of surfaces and colloids2016
Single Microbubble Measurements of Lipid Monolayer Viscoelastic Properties for Small-Amplitude Oscillations.
Article in Langmuir : the ACS journal of surfaces and colloids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 49 citations in OpenAlex.
- Acoustic characterization of shell and size-engineered submicron contrast agents using attenuation measurements.Ultrasonics sonochemistry · 2026Article
- Tuning the Shell Elasticity of Phospholipid-Coated Microbubbles via Palmitic Acid Doping.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Structure and Stability of Phospholipid-Based Microbubbles Studied Using a Spin Probe.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Effect of Poly(ethylene glycol) Configuration on Microbubble Pharmacokinetics.ACS biomaterials science & engineering · 2024Article
- Quantitative estimation of phospholipid molecules desorbed from a microbubble surface under ultrasound irradiation.Scientific reports · 2023Article
- Targeted Microbubbles for Drug, Gene, and Cell Delivery in Therapy and Immunotherapy.Pharmaceutics · 2023Review
- Material Properties, Dissolution and Time Evolution of PEGylated Lipid-Shelled Microbubbles: Effects of the Polyethylene Glycol Hydrophilic Chain Configurations.Ultrasound in medicine & biology · 2022Article
- Photoacoustic Impulse Response of Lipid-Coated Ultrasound Contrast Agents.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- Hydrodynamic shear dissipation and transmission in lipid bilayers.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- The Impact of Lipid Handling and Phase Distribution on the Acoustic Behavior of Microbubbles.Pharmaceutics · 2021Article
- The effect of size range on ultrasound-induced translations in microbubble populations.The Journal of the Acoustical Society of America · 2020Article
- Changes in microbubble dynamics upon adhesion to a solid surface.Applied physics letters · 2020Article
- Phospholipid Oxygen Microbubbles for Image-Guided Therapy.Nanotheranostics · 2020Article
- Contrast enhanced ultrasound imaging by nature-inspired ultrastable echogenic nanobubbles.Nanoscale · 2019Article
- Preserving the Integrity of Surfactant-Stabilized Microbubble Membranes for Localized Oxygen Delivery.Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Plane-Wave Contrast Imaging: A Radiation Force Point of View.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2018Article
- Reverse engineering the ultrasound contrast agent.Advances in colloid and interface science · 2018Review
- Photoacoustic technique to measure temperature effects on microbubble viscoelastic properties.Applied physics letters · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Lipid monolayer rheology plays an important role in a variety of interfacial phenomena, the physics of biological membranes, and the dynamic response of acoustic bubbles and drops. We show here measurements of lipid monolayer elasticity and viscosity for very small strains at megahertz frequency. Individual plasmonic microbubbles of 2-6 μm radius were photothermally activated with a short laser pulse, and the subsequent nanometer-scale radial oscillations during ring-down were monitored by optical scatter. This method provided average dynamic response measurements of single microbubbles. Each microbubble was modeled as an underdamped linear oscillator to determine the damping ratio and eigenfrequency, and thus the lipid monolayer viscosity and elasticity. Our nonisothermal measurement technique revealed viscoelastic trends for different lipid shell compositions. We observed a significant increase in surface elasticity with the lipid acyl chain length for 16 to 20 carbons, and this effect was explained by an intermolecular forces model that accounts for the lipid composition, packing, and hydration. The surface viscosity was found to be equivalent for these lipid shells. We also observed an anomalous decrease in elasticity and an increase in viscosity when increasing the acyl chain length from 20 to 22 carbons. These results illustrate the use of a novel nondestructive optical technique to investigate lipid monolayer rheology in new regimes of frequency and strain, possibly elucidating the phase behavior, as well as how the dynamic response of a microbubble can be tuned by the lipid intermolecular forces.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.