ArticleAmerican journal of physical medicine & rehabilitation2017
Complex and Simple Clinical Reaction Times Are Associated with Gait, Balance, and Major Fall Injury in Older Subjects with Diabetic Peripheral Neuropathy.
Article in American journal of physical medicine & rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Impact of Diabetic Neuropathy on Activities of Daily Living, Postural Balance and Risk of Falls - A Systematic Review.Journal of diabetes science and technology · 2022Pooled it
- Gait as a quantitative indicator of the severity of chemotherapy-induced peripheral neuropathy: a pilot study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- ReacStick: Evaluating Executive Function Independent From Level of Education.American journal of physical medicine & rehabilitation · 2026Article
- Clinical estimates of three physiologic capacities explain a majority of unipedal stance time.Aging clinical and experimental research · 2025Article
- Motor planning stage of gait initiation: effects of aging, Parkinson's disease, and associations with cognitive function.Experimental brain research · 2025Article
- Association of intraindividual variability in simple reaction time with balance and falls in older cancer survivors: A secondary analysis.Journal of geriatric oncology · 2025Article
- Diabetic neuropathy: cutting-edge research and future directions.Signal transduction and targeted therapy · 2025Review
- Optimizing Detection and Prediction of Cognitive Function in Multiple Sclerosis With Ambulatory Cognitive Tests: Protocol for the Longitudinal Observational CogDetect-MS Study.JMIR research protocols · 2024Article
- The association of chemotherapy-induced peripheral neuropathy with reduced executive function in chemotherapy-treated cancer survivors: A cross-sectional study.Journal of geriatric oncology · 2024Article
- Executive function is associated with balance and falls in older cancer survivors treated with chemotherapy: A cross-sectional study.Journal of geriatric oncology · 2023Article
- Suppressing a Blocked Balance Recovery Step: A Novel Method to Assess an Inhibitory Postural Response.Brain sciences · 2023Article
- The relationship between clinical measures of cognitive function and grip strength in healthy older adults.BMC geriatrics · 2022Article
- Inhibitory Control and Fall Prevention: Why Stopping Matters.Frontiers in neurology · 2022Article
- Task matters: an investigation on the effect of different secondary tasks on dual-task gait in older adults.BMC geriatrics · 2021Article
- Chemotherapy-induced peripheral neuropathy increases nontraumatic fracture risk in breast cancer survivors.JBMR plus · 2021Article
- Short-latency inhibition mitigates the relationship between conscious movement processing and overly cautious gait.Age and ageing · 2021Article
- Urinary urgency acts as a source of divided attention leading to changes in gait in older adults with overactive bladder.PloS one · 2021Article
- Neurocognitive and Muscular Capacities Are Associated with Frailty in Adults with Cirrhosis.Digestive diseases and sciences · 2020Article
- Frequency and Circumstances of Falls Reported by Ambulatory Unilateral Lower Limb Prosthesis Users: A Secondary Analysis.PM & R : the journal of injury, function, and rehabilitation · 2019Article
- Why Do Individuals with Cirrhosis Fall? A Mechanistic Model for Fall Assessment, Treatment, and Research.Digestive diseases and sciences · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe aim of this work was to identify relationships between complex and simple clinical measures of reaction time (RTclin) and indicators of balance in older subjects with and without diabetic peripheral neuropathy (DPN).
designProspective cohort design. Complex RTclin accuracy, simple RTclin latency, and their ratio were determined using a novel device in 42 subjects (mean ± SD age, 69.1 ± 8.3 yrs), 26 with DPN and 16 without. Dependent variables included unipedal stance time (UST), step width variability and range on an uneven surface, and major fall-related injury over 12 months.
resultsIn the DPN subjects, the ratio of complex RTclin accuracy to simple RTclin latency was strongly associated with longer UST (R/P = 0.653/0.004), and decreased step width variability and range (R/P = -0.696/0.001 and -0.782/<0.001, respectively) on an uneven surface. Additionally, the 2 DPN subjects sustaining major injuries had lower complex RTclin accuracy:simple RTclin latency than those without.
conclusionsThe ratio of complex RTclin accuracy:simple RTclin latency is a potent predictor of UST and frontal plane gait variability in response to perturbations and may predict major fall injury in older subjects with DPN. These short latency neurocognitive measures may compensate for lower limb neuromuscular impairments and provide a more comprehensive understanding of balance and fall risk.
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