Evidence map›Paper›PMID 27551741›Full record

ArticleMolecular pharmaceutics2016

Reduction Sensitive PEG Hydrogels for Codelivery of Antigen and Adjuvant To Induce Potent CTLs.

Chintan H Kapadia, Shaomin Tian, Jillian L Perry, J Christopher Luft, Joseph M DeSimone

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. A nanovaccine for enhancing cellular immunity via cytosolic co-delivery of antigen and polyIC RNA.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Potential applications of nanoparticles in cancer immunotherapy.Human vaccines & immunotherapeutics · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chintan H Kapadia
Shaomin Tian
Jillian L Perry
J Christopher Luft
Joseph M DeSimoneDepartment of Chemical and Biomolecular Engineering, NC State University , Raleigh, North Carolina 27695, United States.
Memorial Sloan Kettering Cancer Center · US

Funding

Translational Nanosystems for Improved Lung Cancer Treatment with Small MoleculesU54CA151652 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DESIMONE, JOSEPH M. · 2010 to 2014
$12.1M
Small Animal Imaging CoreU54CA198999 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, ZIBO · 2015 to 2019
$11.9M
NCI NIH HHS U54 CA151652NCI NIH HHS U54 CA198999
6 · The paper itself

Abstract

Educating our immune system via vaccination is an attractive approach to combat infectious diseases. Eliciting antigen specific cytotoxic T cells (CTLs), CD8

Indexed as

Adjuvants, ImmunologicAnimalsAntigensBone Marrow CellsCancer VaccinesCD8-Positive T-LymphocytesCell ProliferationChromatography, High Pressure LiquidDendritic CellsDynamic Light ScatteringFemaleHydrogelsMiceMice, Inbred C57BLMicroscopy, Electron, ScanningNanoparticlesAdjuvants, ImmunologicAntigensCancer VaccinesCPG-oligonucleotideHydrogelsOligodeoxyribonucleotidesPeptide FragmentsPolyethylene Glycolscancer vaccinecytotoxic T cells (CTL)disulfide linkersnanoparticlespeptide vaccine

Identifiers

PMID27551741
PMCPMC5708121
OpenAlexW2515906198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.