Evidence map›Paper›PMID 27551404›Full record

ArticleAnnals of medicine and surgery (2012)2016

The change of neutrophils/lymphocytes ratio in migraine attacks: A case-controlled study.

Keziban Ucar Karabulut, Tomris Ugur Egercioglu, Mehmet Uyar, Yildiz Ucar

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
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  6. Article
  7. Hematologic Differences Between Migraineurs and Tension-Type Headache Patients.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2023
    Article
  8. Article
  9. Article
  10. Association between tumor necrosis factor alpha and lymphotoxin alpha gene polymorphisms and migraine occurrence among Jordanians.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  11. PACAP Induces Light Aversion in Mice by an Inheritable Mechanism Independent of CGRP.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  12. Article
  13. Article
  14. Non-invasively triggered spreading depolarizations induce a rapid pro-inflammatory response in cerebral cortex.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Keziban Ucar KarabulutDepartment of Emergency Medicine, Baskent University, Faculty of Medicine, Ankara, Turkey.
Tomris Ugur EgerciogluDepartment of Neurology, Baskent University, Faculty of Medicine, Ankara, Turkey.
Mehmet UyarDepartment of Pubic Health, Necmettin Erbakan University, Meram Medical Faculty, Konya, Turkey.
Yildiz UcarDepartment of Pulmonary Dissease, Diyarbakır Memorial Hospital, Diyarbakır, Turkey.
Başkent University · TRDiyarbakır Askeri Hastanesi · TRNecmettin Erbakan University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAs commonly seen symptoms, headaches are among the most frequently encountered health challenges in emergency rooms by healthcare professionals. Among one of the most commonly seen and primary headaches is migraine. Migraines are mostly accompanied by functional deficits.

aimsTo observe the changes of neutrophil/lymphocyte ratio occurring during migraine attacks.

methodThis is a retrospective study where hospital records of patients previously diagnosed with migraine and admitted to the emergency with the complaints of attacks between May 2014 and January 2015 were investigated. All patients in the study were evaluated as to age, gender and complete blood count. Additionally, a healthy control group was formed with individuals with no disorders. By also evaluating the same features in the controls, the values found in the patients and controls alike were compared.

resultsThe values of white blood cell, lymphocyte, neutrophil, hemoglobin, thrombocyte and neutrophil/lymphocyte ratio determined in the patient group (n = 92) were statistically compared with those of the controls (n = 67). Neutrophil/lymphocyte ratio during the attacks was found higher in the patients, compared to the controls.

conclusionNeutrophil/lymphocyte ratio is a sign of inflammation, and we consider that this ratio will also increase during migraine attacks, as with other inflammatory and acute processes.

Indexed as

HeadachesInflammationMigraineNeutrophil/lymphocyte ratio

Identifiers

PMID27551404
PMCPMC4983641
OpenAlexW2497337427

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.