Trial reportHypertension (Dallas, Tex. : 1979)2016
The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial).
Registry-linked trialAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph
Trial report in Hypertension (Dallas, Tex. : 1979), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01192412 (The CHIPS Trial), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The CHIPS Trial (Control of Hypertension In Pregnancy Study)
Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Economic Evaluation of Prenatal and Postpartum Care in Women With Gestational Diabetes and Hypertensive Disorders of Pregnancy: A Systematic Review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2022Pooled it
- Impact of Antihypertensive Treatment on Maternal and Perinatal Outcomes in Pregnancy Complicated by Chronic Hypertension: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2017Pooled it
- Trial
- Toward personalized management of chronic hypertension in pregnancy.American journal of obstetrics and gynecology · 2022Review
- Blood pressure change across pregnancy in white British and Pakistani women: analysis of data from the Born in Bradford cohort.Scientific reports · 2019Article
- Resistant Hypertension in Pregnancy: How to Manage?Current hypertension reports · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Rashid J AhmedFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Amiram GafniFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Eileen K HuttonFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Zheng Jing HuFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Eleanor PullenayegumFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Peter von DadelszenFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Evelyne ReyFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Susan RossFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Elizabeth AsztalosFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Kellie E MurphyFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Jennifer MenziesFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
J Johanna SanchezFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Wessel GanzevoortFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Michael HelewaFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Shoo K LeeFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Terry LeeFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Alexander G LoganFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Jean-Marie MoutquinFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Joel SingerFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Jim G ThorntonFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Ross WelchFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Laura A MageeFrom the Department of Obstetrics and Gynecology (R.J.A., E.K.H.), Department of Clinical Epidemiology and Biostatistics, Centre for Health Economics and Policy Analysis (A.G.), and Department of Mathematics and Statistics (Z.J.H.), McMaster University, Hamilton, Ontario, Canada; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Hospital for Sick Children, Ontario, Canada (E.P.); Department of Obstetrics and Gynaecology, St. George's University of London, United Kingdom (P.v.D.); Departments of Medicine (E.R.) and Obstetrics and Gynaecology (E.R.), University of Montreal, Quebec, Canada; Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada (S.R.); Departments of Paediatrics (E.A.) and Obstetrics and Gynecology (E.A.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada; Departments of Obstetrics and Gynecology (K.E.M.) and Medicine (K.E.M., A.G.L.), University of Toronto, Mount Sinai Hospital, Ontario, Canada; Department of Obstetrics and Gynaecology (J.M.), Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute (T.L.), and School of Population and Public Health (J.S.), University of British Columbia, Vancouver, Canada; Clinical Trial Services, The Centre for Mother, Infant and Child Research, Sunnybrook Research Institute, Toronto, Ontario, Canada (J.J.S.); Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands (W.G.); Department of Obstetrics, Gynecology, and Reproductive Sciences, Women's Health, University of Manitoba, Winnipeg, Canada (M.H.); Division of Neonatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada (S.K.L.); Department of Obstetrics and Gynecology, Université de Sherbrooke, Québec, Canada (J.-M.M.); Department of Obstetrics and Gynaecology, University of Nottingham, Nottingham City Hospital, United Kingdom (J.G.T.); Department of Obstetr
Funding
CIHR
Abstract
unlabelledThe CHIPS randomized controlled trial (Control of Hypertension in Pregnancy Study) found no difference in the primary perinatal or secondary maternal outcomes between planned "less tight" (target diastolic 100 mm Hg) and "tight" (target diastolic 85 mm Hg) blood pressure management strategies among women with chronic or gestational hypertension. This study examined which of these management strategies is more or less costly from a third-party payer perspective. A total of 981 women with singleton pregnancies and nonsevere, nonproteinuric chronic or gestational hypertension were randomized at 14 to 33 weeks to less tight or tight control. Resources used were collected from 94 centers in 15 countries and costed as if the trial took place in each of 3 Canadian provinces as a cost-sensitivity analysis. Eleven hospital ward and 24 health service costs were obtained from a similar trial and provincial government health insurance schedules of medical benefits. The mean total cost per woman-infant dyad was higher in less tight versus tight control, but the difference in mean total cost (DM) was not statistically significant in any province: Ontario ($30 191.62 versus $24 469.06; DM $5723, 95% confidence interval, -$296 to $12 272; P=0.0725); British Columbia ($30 593.69 versus $24 776.51; DM $5817; 95% confidence interval, -$385 to $12 349; P=0.0725); or Alberta ($31 510.72 versus $25 510.49; DM $6000.23; 95% confidence interval, -$154 to $12 781; P=0.0637). Tight control may benefit women without increasing risk to neonates (as shown in the main CHIPS trial), without additional (and possibly lower) cost to the healthcare system. CLINICAL
trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT01192412.
Indexed as
Health Care CostsAntihypertensive AgentsBlood Pressure DeterminationCanadaCost-Benefit AnalysisDelivery, ObstetricFemaleHospitalizationHumansHypertension, Pregnancy-InducedInfant, NewbornInternationalityLength of StayPregnancyAntihypertensive Agentsblood pressurecost analysishealth policyhypertensionpregnancyrandomized controlled trials
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Read underepoch 390
Registered trials
NCT01192412ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.