Evidence map›Paper›PMID 27550526›Full record

Observational studyThe British journal of surgery2016

Role of omentectomy as part of radical surgery for gastric cancer.

E J Jongerius, D Boerma, K A Seldenrijk, S L Meijer, J J G Scheepers, F Smedts, S M Lagarde, O Balague Ponz, M I van Berge Henegouwen, J W van Sandick and 1 more

2 registry-linked trialsOpen access · greenAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in The British journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 6 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02050659 completednot on this map

Omentectomy in Radical Gastrectomy for Gastric Cancer Trial

TypeobservationalSponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Ran2012 to 2014Enrolled100ConditionsOmentum, Stomach Neoplasms
NCT05238584 naunknown statusnot on this mapstarted 2022, after this paper: background citation

A Multicenter, Prospective, Randomized Trial to Evaluate the Role of Total Versus Partial Omentectomy in the Treatment of Tis - T3 Gastric Cancer.

TypeinterventionalSponsorUniversity of DebrecenRan2022 to 2024Enrolled300ConditionsStomach Neoplasms, Interleukin, Stomach Cancer, Gastric CancerArmsPartial omentectomy
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 6 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
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  7. Pattern of lymph node metastases in gastric cancer: a side-study of the multicenter LOGICA-trial.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022
    Trial
  8. Article
  9. Article
  10. Current debate in gastric cancer surgery: Omentectomy?World journal of gastrointestinal surgery · 2025
    Review
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Review
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  18. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

E J JongeriusDepartments of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
D BoermaDepartments of Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.
K A SeldenrijkDepartments of Pathology, St Antonius Hospital, Nieuwegein, The Netherlands.
S L MeijerDepartments of Pathology, Academic Medical Centre, Amsterdam, The Netherlands.
J J G ScheepersDepartments of Surgery, Reinier de Graaf Gasthuis, Delft, The Netherlands.
F SmedtsDepartments of Pathology, Reinier de Graaf Gasthuis, Delft, The Netherlands.
S M LagardeDepartments of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
O Balague PonzDepartments of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
M I van Berge HenegouwenDepartments of Surgery, Academic Medical Centre, Amsterdam, The Netherlands.
J W van SandickDepartments of Surgery, Netherlands Cancer Institute, Amsterdam, The Netherlands.
S S GisbertzDepartments of Surgery, Academic Medical Centre, Amsterdam, The Netherlands. s.s.gisbertz@amc.nl.
Academic Medical Center · NLReinier de Graaf Hospital · NLSt. Antonius Ziekenhuis · NLThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA complete omentectomy is recommended as part of radical (sub)total gastrectomy for gastric cancer, but there is little evidence to suggest any survival benefit. The aim of this study was to evaluate the incidence of, and risk factors for, metastases in the greater omentum in patients undergoing gastrectomy for gastric cancer.

methodsThis was a multicentre prospective cohort study (OMEGA trial) of consecutive patients with gastric cancer undergoing (sub)total gastrectomy with complete en bloc omentectomy and modified D2 lymphadenectomy. After resection, the omentum was separated from the gastrectomy specimen distal to the gastroepiploic vessels and sent separately for pathological examination. The primary endpoint was the presence of metastases in the greater omentum.

resultsOf 100 included patients, five (5·0 per cent) had metastases in the greater omentum. Pathology results showed advanced tumours in all five (pT4b N1 M1, pT4b N2 M1, ypT4a N1 M1, ypT3 N2 M0, ypT3 N3 M0). The resection was microscopically non-radical at the proximal (3) or distal (2) resection margin in all of these patients. Metastases in the greater omentum correlated significantly with a microscopically non-radical resection, tumour expansion in the oesophagus or duodenum, linitis plastica or a proximal gastric tumour with diameter of at least 5 cm, stage III-IV disease and (y)pM1 category.

conclusionIn resectable gastric cancer, the incidence of metastases in the greater omentum is low, and when present associated with advanced disease and non-radical features. Thus, omentectomy as part of a radical gastrectomy may be omitted. REGISTRATION NUMBER: NCT02050659 ( http://www.clinicaltrials.gov).

Indexed as

AdultAgedAged, 80 and overConversion to Open SurgeryFemaleGastrectomyHumansLaparoscopyMaleMiddle AgedNeoplasm MetastasisOmentumProspective StudiesStomach NeoplasmsTreatment Outcome

Identifiers

PMID27550526
OpenAlexW2511498241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.