ArticleOdontology2017
Functional effects of cold stimulation on taste perception in humans.
Article in Odontology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 15 citations in OpenAlex.
- Taste Preferences at Different Ambient Temperatures and Associated Changes in Gut Microbiota and Body Weight in Mice.Foods (Basel, Switzerland) · 2024Article
- The orotrigeminal system.Handbook of clinical neurology · 2019Review
- Awareness of dysgeusia and gustatory tests in patients undergoing chemotherapy for breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
- Extraoral Taste Receptor Discovery: New Light on Ayurvedic Pharmacology.Evidence-based complementary and alternative medicine : eCAM · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thermal modulation of signaling pathways leads to excitation of taste receptor cells, but the underlying mechanisms remain unclear. Furthermore, it has long been known that there are contrast effects in various senses. In this study, we investigated cold-taste contrast and the relationship between taste and somatosensation. We lowered intraoral temperature using cold stimulus as a pretreatment, then returned to normal temperature in 249 healthy subjects, before administering room temperature taste-stimulating solutions to investigate changes in sensitivity to the four basic tastes (Sweet, Salt, Sour, and Bitter). Statistical comparisons of taste recognition thresholds before and after cold stimulus showed increased taste sensitivity for all four basic tastes. After categorizing different levels of pre-cold stimulus taste sensitivity into groups and comparing changes in sensitivity to the four basic tastes before and after stimulus, we found that the lower the sensitivity to the four basic tastes, the greater the increase in sensitivity induced by cold stimulus. These findings suggest that taste and low temperature send afferent signals which cause interaction in the afferent pathways between the peripheral and central nervous systems. Cold stimulus may offer one possible treatment strategy for dysgeusia.
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Registered trials
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