Evidence map›Paper›PMID 27550078›Full record

ArticleMagnetic resonance in medicine2016

In vivo diffusion-tensor MRI of the human heart on a 3 tesla clinical scanner: An optimized second order (M2) motion compensated diffusion-preparation approach.

Christopher Nguyen, Zhaoyang Fan, Yibin Xie, Jianing Pang, Peter Speier, Xiaoming Bi, Jon Kobashigawa, Debiao Li

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Christopher NguyenBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Zhaoyang FanBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Yibin XieBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Jianing PangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Peter SpeierSiemens Healthcare GmbH, Erlangen, Germany.
Xiaoming BiSiemens Healthcare, Los Angeles, California, USA.
Jon KobashigawaHeart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Debiao LiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. debiao.li@cshs.org.
Cedars-Sinai Medical Center · USSiemens Healthcare (Germany) · DESiemens Healthcare (United States) · US

Funding

Whole-Heart Myocardial Blood Flow Quantification Using MRIR01HL124649 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI LI, DEBIAO · 2015 to 2018
$3.3M
Clinically Translatable Cardiac Diffusion MR for Non-Contrast Characterization ofF31EB018152 · NIBIB · CEDARS-SINAI MEDICAL CENTER · PI NGUYEN, CHRISTOPHER T · 2014 to 2014
$28k
NHLBI NIH HHS R01 HL124649NIBIB NIH HHS F31 EB018152
6 · The paper itself

Abstract

purposeTo optimize a diffusion-prepared balanced steady-state free precession cardiac MRI (CMR) technique to perform diffusion-tensor CMR (DT-CMR) in humans on a 3 Tesla clinical scanner

methodsA previously developed second order motion compensated (M2) diffusion-preparation scheme was significantly shortened (40%) yielding sufficient signal-to-noise ratio for DT-CMR imaging. In 20 healthy volunteers and 3 heart failure (HF) patients, DT-CMR was performed comparing no motion compensation (M0), first order motion compensation (M1), and the optimized M2. Mean diffusivity (MD), fractional anisotropy (FA), helix angle (HA), and HA transmural slope (HATS) were calculated. Reproducibility and success rate (SR) were investigated.

resultsM2-derived left ventricular (LV) MD, FA, and HATS (1.4 ± 0.2 μm

conclusionThe proposed M2 DT-CMR reproducibly yielded bulk motion robust estimations of mean LV MD, FA, HA, and HATS on a 3T clinical scanner. Magn Reson Med 76:1354-1363, 2016. © 2016 International Society for Magnetic Resonance in Medicine.

Indexed as

ArtifactsAdultAgedAlgorithmsCardiac-Gated Imaging TechniquesDiffusion Tensor ImagingFemaleHeartHeart FailureHumansImage EnhancementImage Interpretation, Computer-AssistedMaleMotionReproducibility of ResultsSensitivity and SpecificitybSSFPcardiovascular MRIdiffusion preparationdiffusion tensorDT-CMRDTIDT-MRIM2second order motion compensation

Identifiers

PMID27550078
PMCPMC5067209
OpenAlexW2512162748

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.