Evidence map›Paper›PMID 27550052›Full record

ArticleNanoscale research letters2016

Sustained, Controlled and Stimuli-Responsive Drug Release Systems Based on Nanoporous Anodic Alumina with Layer-by-Layer Polyelectrolyte.

Maria Porta-I-Batalla, Chris Eckstein, Elisabet Xifré-Pérez, Pilar Formentín, J Ferré-Borrull, Lluis F Marsal

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Review
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  5. Toxicity of Carboplatin-Niosomal Nanoparticles in a Brain Cancer Cell Line.Asian Pacific journal of cancer prevention : APJCP · 2023
    Article
  6. Review
  7. Tunable PropertiesMaterials (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Evolution of drug-eluting biomedical implants for sustained drug delivery.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2021
    Review
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maria Porta-I-BatallaDepartment of Electronic, Electric and Automatics Engineering, Universitat Rovira i Virgili, Avda. Països Catalans 26, 43007, Tarragona, Spain.
Chris EcksteinDepartment of Electronic, Electric and Automatics Engineering, Universitat Rovira i Virgili, Avda. Països Catalans 26, 43007, Tarragona, Spain.
Elisabet Xifré-PérezDepartment of Electronic, Electric and Automatics Engineering, Universitat Rovira i Virgili, Avda. Països Catalans 26, 43007, Tarragona, Spain.
Pilar FormentínDepartment of Electronic, Electric and Automatics Engineering, Universitat Rovira i Virgili, Avda. Països Catalans 26, 43007, Tarragona, Spain.
J Ferré-BorrullDepartment of Electronic, Electric and Automatics Engineering, Universitat Rovira i Virgili, Avda. Països Catalans 26, 43007, Tarragona, Spain.
Lluis F MarsalDepartment of Electronic, Electric and Automatics Engineering, Universitat Rovira i Virgili, Avda. Països Catalans 26, 43007, Tarragona, Spain. lluis.marsal@urv.cat.ORCID http://orcid.org/0000-0002-5976-1408
Universitat Rovira i Virgili · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Controlled drug delivery systems are an encouraging solution to some drug disadvantages such as reduced solubility, deprived biodistribution, tissue damage, fast breakdown of the drug, cytotoxicity, or side effects. Self-ordered nanoporous anodic alumina is an auspicious material for drug delivery due to its biocompatibility, stability, and controllable pore geometry. Its use in drug delivery applications has been explored in several fields, including therapeutic devices for bone and dental tissue engineering, coronary stent implants, and carriers for transplanted cells. In this work, we have created and analyzed a stimuli-responsive drug delivery system based on layer-by-layer pH-responsive polyelectrolyte and nanoporous anodic alumina. The results demonstrate that it is possible to control the drug release using a polyelectrolyte multilayer coating that will act as a gate.

Indexed as

DoxorubicinDrug deliveryElectrochemical anodizationNanoporous aluminaStimuli-responsive release

Identifiers

PMID27550052
PMCPMC4993726
OpenAlexW2518627595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.