Evidence map›Paper›PMID 27549770›Full record

ArticleGigaScience2016

Chromosomer: a reference-based genome arrangement tool for producing draft chromosome sequences.

Gaik Tamazian, Pavel Dobrynin, Ksenia Krasheninnikova, Aleksey Komissarov, Klaus-Peter Koepfli, Stephen J O'Brien

Abstract read
In one paragraph

Article in GigaScience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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  14. Genome Analysis ofGenes · 2021
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gaik TamazianTheodosius Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, Sredniy Prospekt 41A, St. Petersburg, 199004, Russia. mail@gtamazian.com.ORCID 0000-0002-2931-1123
Pavel DobryninTheodosius Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, Sredniy Prospekt 41A, St. Petersburg, 199004, Russia.
Ksenia KrasheninnikovaTheodosius Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, Sredniy Prospekt 41A, St. Petersburg, 199004, Russia.
Aleksey KomissarovTheodosius Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, Sredniy Prospekt 41A, St. Petersburg, 199004, Russia.
Klaus-Peter KoepfliTheodosius Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, Sredniy Prospekt 41A, St. Petersburg, 199004, Russia.
Stephen J O'BrienTheodosius Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, Sredniy Prospekt 41A, St. Petersburg, 199004, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the number of sequenced genomes rapidly increases, chromosome assembly is becoming an even more crucial step of any genome study. Since de novo chromosome assemblies are confounded by repeat-mediated artifacts, reference-assisted assemblies that use comparative inference have become widely used, prompting the development of several reference-assisted assembly programs for prokaryotic and eukaryotic genomes.

findingsWe developed Chromosomer - a reference-based genome arrangement tool, which rapidly builds chromosomes from genome contigs or scaffolds using their alignments to a reference genome of a closely related species. Chromosomer does not require mate-pair libraries and it offers a number of auxiliary tools that implement common operations accompanying the genome assembly process.

conclusionsDespite implementing a straightforward alignment-based approach, Chromosomer is a useful tool for genomic analysis of species without chromosome maps. Putative chromosome assemblies by Chromosomer can be used in comparative genomic analysis, genomic variation assessment, potential linkage group inference and other kinds of analysis involving contig or scaffold mapping to a high-quality assembly.

Indexed as

Chromosome MappingContig MappingGenomeSequence AlignmentSoftwareAlignmentChromosome assemblyReference-assisted assembly

Identifiers

PMID27549770
PMCPMC4994284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.