Evidence map›Paper›PMID 27549636›Full record

ArticleThe American journal of tropical medicine and hygiene2016

Development of Two FhSAP2 Recombinant-Based Assays for Immunodiagnosis of Human Chronic Fascioliasis.

Sun Hee Shin, Angel Hsu, Holly M Chastain, Lorna A Cruz, Eric S Elder, Sarah G H Sapp, Isabel McAuliffe, Ana M Espino, Sukwan Handali

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. AdultASM case reports · 2026
    Article
  2. Review
  3. Diagnosis of Human Trematode Infections.Advances in experimental medicine and biology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Parasitic Infection Surveillance in Mississippi Delta Children.The American journal of tropical medicine and hygiene · 2020
    Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sun Hee ShinDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Angel HsuEmory College, Emory University, Atlanta, Georgia.
Holly M ChastainDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Lorna A CruzLaboratory of Immunology and Molecular Parasitology, Department of Microbiology, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico.
Eric S ElderDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Sarah G H SappUniversity of Georgia, Athens, Georgia.
Isabel McAuliffeDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Ana M EspinoLaboratory of Immunology and Molecular Parasitology, Department of Microbiology, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico.
Sukwan HandaliDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia. ahi0@cdc.gov.
Centers for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the United States, infection with Fasciola hepatica has been identified as an emerging disease, primarily in immigrants, refugees, and travelers. The laboratory test of choice for diagnosis of fascioliasis is detection of disease specific antibodies, most commonly uses excretory-secretory antigens for detection of IgG antibodies. Recently, recombinant proteins such as F. hepatica antigen (FhSAP2) have been used to detect IgG antibodies. The glutathione S-transferase (GST)-FhSAP2 recombinant antigen was used to develop Western blot (WB) and fluorescent bead-based (Luminex) assays to detect F. hepatica total IgG and IgG

Indexed as

AnimalsAntibodies, HelminthAntigens, HelminthBlotting, WesternCase-Control StudiesChronic DiseaseCross ReactionsFasciola hepaticaFascioliasisFluorescent Antibody TechniqueGlutathione TransferaseHookworm InfectionsHumansImmunoglobulin GSchistosomiasis japonicaSensitivity and SpecificityAntibodies, HelminthAntigens, HelminthGlutathione TransferaseImmunoglobulin G

Identifiers

PMID27549636
PMCPMC5062787
OpenAlexW2508383312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.