Evidence map›Paper›PMID 27549634›Full record

ArticleThe American journal of tropical medicine and hygiene2016

Successful Treatment of Cutaneous Leishmaniasis with Topical Paramomycin in a Child After Treatment Failure with Systemic Fluconazole.

Anila Chacko, Marissa Joseph, Timothy Feltis, Shaun K Morris

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anila ChackoDivision of Infectious Diseases, Hospital for Sick Children, Toronto, Canada.
Marissa JosephDepartment of Pediatrics, University of Toronto, Toronto, Canada. Division of Dermatology, Women's College Hospital, University of Toronto, Toronto, Canada.
Timothy FeltisLifelabs Medical Laboratory Services, Toronto, Canada.
Shaun K MorrisDivision of Infectious Diseases, Hospital for Sick Children, Toronto, Canada. Department of Pediatrics, University of Toronto, Toronto, Canada. Centre for Global Child Health, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children Research Institute, Toronto, Canada. shaun.morris@sickkids.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is challenging to find safe, nonscarring and noninvasive treatment of facial cutaneous leishmaniasis (CL) in children. Herein, we report a child with CL from a region endemic for Leishmania tropica, whose lesion persisted after treatment with oral fluconazole but responded to topical paromomycin. Paromomycin should be considered early for treatment of Old World CL and is a well-tolerated and effective mode of therapy for facial lesions.

Indexed as

Administration, OralAdministration, TopicalAntiprotozoal AgentsChild, PreschoolFluconazoleForeheadHumansLeishmaniasis, CutaneousLeishmania tropicaMaleParomomycinTreatment OutcomeAntiprotozoal AgentsFluconazoleParomomycin

Identifiers

PMID27549634
PMCPMC5062774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.