SynthesisScientific reports2016
Sleep Duration and the Risk of Fatty Liver Disease: A Systematic Review and Meta-analysis.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sleep duration and health outcomes: an umbrella review.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Sleep problems and injury risk among juveniles: A systematic review and meta-analysis of observational studies.Scientific reports · 2017Pooled it
- Association between sleep duration and risk of nonalcoholic fatty liver disease: A systematic review and meta-analysis.Preventive medicine reports · 2025Review
- Sleep and Cardiometabolic Health: A Narrative Review of Epidemiological Evidence, Mechanisms, and Interventions.International journal of general medicine · 2025Review
- Circadian Deregulation: Back Facing the Sun Toward Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Development.Nutrients · 2024Review
- Shift work and non-alcoholic fatty liver disease in young, healthy workers.Scientific reports · 2024Article
- Associations of activity, sedentary and sleep behaviors with prevalent steatotic liver disease in middle-aged and older adults: the ELSA-Brasil study.Journal of activity, sedentary and sleep behaviors · 2024Article
- Sleep and liver function biomarkers in relation to risk of incident liver cancer: a nationwide prospective cohort study.BMC medicine · 2024Article
- Sleep characteristics of middle-aged adults with non-alcoholic fatty liver disease: findings from the Shahrekord PERSIAN cohort study.BMC public health · 2023Article
- Role of Circadian Clock on the Pathogenesis and Lifestyle Management in Non-Alcoholic Fatty Liver Disease.Nutrients · 2022Review
- Decrease in Sleep Duration and Poor Sleep Quality over Time Is Associated with an Increased Risk of Incident Non-Alcoholic Fatty Liver Disease.Journal of personalized medicine · 2022Article
- Investigating the Association Between Seven Sleep Traits and Nonalcoholic Fatty Liver Disease: Observational and Mendelian Randomization Study.Frontiers in genetics · 2022Article
- Sleep disorder in patients with chronic liver disease: a narrative review.Journal of thoracic disease · 2020Review
- Autoimmune hepatitis, fatty liver, and Fukushima.Fukushima journal of medical science · 2019Review
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have reported inconsistent results on the association between sleep duration and the risk of fatty liver disease (FLD). Thus, we quantitatively evaluated this association by performing a systematic review and meta-analysis, based on a comprehensive electronic search in databases of PubMed, Web of Science, EMBASE, ClinicalTrials.gov, Wanfangdata and Chinese National Knowledge Infrastructure (CNKI) (updated to April 2016). Multivariate adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs) were extracted and pooled by using a random-effects model. Eight eligible studies involving 97,371 participants were included. We found that neither short nor long sleep duration was significantly related with FLD risk. For short sleep duration, the pooled OR was 1.17 (95% CI = 0.98-1.38), and for long sleep duration, the pooled OR was 1.01 (95% CI = 0.72-1.41). Subgroup analyses by sex, outcome, and exposure reference also did not identify any effect of sleep duration on FLD onset. In summary, our findings suggested that short or long sleep duration was not significantly associated with FLD risk. Further cohort studies with refined designs are still warranted to validate our results.
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Registered trials
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