ArticleGenome biology2016
Digitally deconvolving the tumor microenvironment.
Article in Genome biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Molecular classification of geriatric breast cancer displays distinct senescent subgroups of prognostic significance.Molecular therapy. Nucleic acids · 2024Article
- A bioinformatics approach to identify a disulfidptosis-related gene signature for prognostic implication in colon adenocarcinoma.Scientific reports · 2023Article
- Pan-Cancer Study of SHC-Adaptor Protein 1 (SHC1) as a Diagnostic, Prognostic and Immunological Biomarker in Human Cancer.Frontiers in genetics · 2022Article
- Exosomal miR-1228 From Cancer-Associated Fibroblasts Promotes Cell Migration and Invasion of Osteosarcoma by Directly Targeting SCAI.Oncology research · 2019Article
- New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx.PLoS computational biology · 2019Article
- Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas.PloS one · 2019Article
- Integrative analysis of the inter-tumoral heterogeneity of triple-negative breast cancer.Scientific reports · 2018Article
- Computational de novo discovery of distinguishing genes for biological processes and cell types in complex tissues.PloS one · 2018Article
- Estimation of immune cell content in tumour tissue using single-cell RNA-seq data.Nature communications · 2017Article
- Cancer Cell-Autonomous Parainflammation Mimics Immune Cell Infiltration.Cancer research · 2017Article
- Data normalization considerations for digital tumor dissection.Genome biology · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Understanding a tumor's complex cellular heterogeneity will be crucial for the development of better treatment strategies. A new study suggests a novel method for the in silico dissociation of solid tumors and presents novel insights that have implications for immunotherapy in cancer.Please see the related Research article: www.dx.doi.org/10.1186/s13059-016-1028-7 .
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.