Evidence map›Paper›PMID 27549153›Full record

ArticleBMC gastroenterology2016

Prevalence of hepatitis B and clinical outcomes in inflammatory bowel disease patients in a viral-endemic region.

Heyson C H Chan, Vincent W S Wong, Grace L H Wong, Whitney Tang, Justin C Y Wu, Siew C Ng

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. IBD barriers across the continents - East Asia.Therapeutic advances in gastroenterology · 2023
    Review
  3. Article
  4. Article
  5. Review
  6. Emerging biologics in inflammatory bowel disease.Journal of gastroenterology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heyson C H ChanDepartment of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Science, State Key Laboratory of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Vincent W S WongDepartment of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Science, State Key Laboratory of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Grace L H WongDepartment of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Science, State Key Laboratory of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Whitney TangDepartment of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Science, State Key Laboratory of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Justin C Y WuDepartment of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Science, State Key Laboratory of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Siew C NgDepartment of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Science, State Key Laboratory of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China. siewchienng@cuhk.edu.hk.
Chinese University of Hong Kong · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known of the prevalence of hepatitis B virus (HBV) infection and its effect on choice of therapy and disease course in patients with inflammatory bowel disease (IBD). We assessed the prevalence of HBV in Hong Kong as well as determinants of altered transaminases, effects of HBV infection on therapeutic strategy and clinical course in IBD.

methodsIn this retrospective cohort, hepatitis B surface antigen (HBsAg), liver function tests, and IBD disease characteristics were recorded. Logistic regression was used to identify factors associated with altered transaminases.

resultsFour hundred six IBD patients were recruited. HBV infection was found in 5.7 % patients in Hong Kong. The use of steroids (OR, 2.52; p = 0.010) and a previous history of surgery (OR 2.33; p = 0.026) were associated with altered transaminases in IBD. There was no significant difference in disease control and use of IBD medication between HBsAg-positive and HBsAg-negative IBD patients.

conclusionThe prevalence of HBV among patients with IBD in Hong Kong (5.7 %) is similar to that of general population (~7 %). There was no difference in disease control and use of IBD medication between subjects with or without HBV.

Indexed as

Adrenal Cortex HormonesAdultAntiviral AgentsDNA, ViralFemaleHepatitis BHepatitis B Surface AntigensHepatitis B virusHong KongHumansImmunosuppressive AgentsInflammatory Bowel DiseasesLiverLiver Function TestsMaleMiddle AgedAdrenal Cortex HormonesAntiviral AgentsDNA, ViralHepatitis B Surface AntigensImmunosuppressive AgentsTransaminasesHepatitis BImmunosuppressionInflammatory bowel disease

Identifiers

PMID27549153
PMCPMC4994386
OpenAlexW2513482243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.