ArticleScientific reports2016
Drone exposure to the systemic insecticide Fipronil indirectly impairs queen reproductive potential.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Unraveling pesticide impacts on pollinators: a global challenge for sustainable crop protection.Die Naturwissenschaften · 2026Review
- Fluvalinate accumulation in the beehive environment and its effects on semen quality and gene expression of drones under field conditions.Ecotoxicology (London, England) · 2026Article
- Impact of the pesticide fipronil on honey quality and the survival of Apis mellifera bees.Environmental science and pollution research international · 2026Article
- Effects of Ionizing Radiation onToxics · 2025Article
- Effects of pesticides on sperm quality in honey bee (Apis mellifera L.) drones.Veterinary research communications · 2025Article
- Unintended consequences of antibiotic use in beekeeping: drone health as a potential vulnerability.Animal microbiome · 2025Article
- Article
- Article
- Current Insights into Sublethal Effects of Pesticides on Insects.International journal of molecular sciences · 2024Review
- Re-using food resources from failed honey bee (Apis mellifera L.) colonies and their impact on colony queen rearing capacity.Scientific reports · 2023Article
- A GABA Receptor Modulator and Semiochemical Compounds Evidenced Using Volatolomics as Candidate Markers of Chronic Exposure to Fipronil inMetabolites · 2023Article
- Indirect exposure to insect growth disruptors affects honey bee (Apis mellifera) reproductive behaviors and ovarian protein expression.PloS one · 2023Article
- The Influence of Body Weight on Semen Parameters inInsects · 2022Article
- Drone honey bees are disproportionately sensitive to abiotic stressors despite expressing high levels of stress response proteins.Communications biology · 2022Article
- Side-effects of pesticides on non-target insects in agriculture: a mini-review.Die Naturwissenschaften · 2022Review
- Variation in the reproductive quality of honey bee males affects their age of flight attempt.PeerJ · 2022Article
- Reproductive and Morphological Quality of Commercial Honey Bee (Hymenoptera: Apidae) Drones in the United States.Journal of insect science (Online) · 2021Article
- Effects of Insecticides and Microbiological Contaminants onMolecules (Basel, Switzerland) · 2021Review
- Review
- Toxicity assessment of chronic exposure to common insecticides and bee medications on colony development and drones sperm parameters.Ecotoxicology (London, England) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A species that requires sexual reproduction but cannot reproduce is doomed to extinction. The important increasing loss of species emphasizes the ecological significance of elucidating the effects of environmental stressors, such as pesticides, on reproduction. Despite its special reproductive behavior, the honey bee was selected as a relevant and integrative environmental model because of its constant and diverse exposure to many stressors due to foraging activity. The widely used insecticide Fipronil, the use of which is controversial because of its adverse effects on honey bees, was chosen to expose captive drones in hives via syrup contaminated at 0.1 μg/L and gathered by foragers. Such environmental exposure led to decreased spermatozoa concentration and sperm viability coupled with an increased sperm metabolic rate, resulting in drone fertility impairment. Subsequently, unexposed queens inseminated with such sperm exhibited fewer spermatozoa with lower viability in their spermatheca, leaving no doubt about the detrimental consequences for the reproductive potential of queens, which are key for colony sustainability. These findings suggest that pesticides could contribute to declining honey bee populations through fertility impairment, as exemplified by Fipronil. More broadly, reproductive disorders should be taken into consideration when investigating the decline of other species.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.