Evidence map›Paper›PMID 27548839›Full record

Trial reportPsycho-oncology2017

Qigong/tai chi for sleep and fatigue in prostate cancer patients undergoing radiotherapy: a randomized controlled trial.

Jennifer L McQuade, Sarah Prinsloo, David Z Chang, Amy Spelman, Qi Wei, Karen Basen-Engquist, Carol Harrison, Zonghao Zhang, Debra Kuban, Andrew Lee and 1 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psycho-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04019301 (Caring for Caregivers With Mind-body Exercise), which is not on this map. Cited by 43 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 22 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04019301 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Caring for Caregivers With Mind-body Exercise

TypeinterventionalSponsorUniversity of HoustonRan2019 to 2022Enrolled47ConditionsCaregiver Distress, Physical Function, Quality of LifeArmsBaduanjin Qigong, Community-based, Baduanjin Qigong, Internet-based
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 22 syntheses or guidelines pooled it, 88 citations in OpenAlex.

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  6. Management of Fatigue in Adult Survivors of Cancer: ASCO-Society for Integrative Oncology Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
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  14. Exercise Therapy and Radiation Therapy for Cancer: A Systematic Review.International journal of radiation oncology, biology, physics · 2021
    Pooled it
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  19. Ameliorative effects of Tai Chi on cancer-related fatigue: a meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jennifer L McQuadeDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sarah PrinslooDepartment of Palliative Care, Rehabilitation Medicine, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
David Z ChangVirginia Oncology Associates and Department of Medicine, Eastern Virginia Medical School, Newport News, VA, USA.
Amy SpelmanDepartment of Palliative Care, Rehabilitation Medicine, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Qi WeiDepartment of Palliative Care, Rehabilitation Medicine, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Karen Basen-EngquistDepartment of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Carol HarrisonDepartment of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zonghao ZhangSchool of Physical Education and Sports, Soochow University, Suzhou, China.
Debra KubanDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Andrew LeeDepartment of Radiation Oncology, Texas Oncology, Irving, TX, USA.
Lorenzo CohenDepartment of Palliative Care, Rehabilitation Medicine, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
The University of Texas MD Anderson Cancer Center · USEastern Virginia Medical School · USSoochow University · CNTexas Oncology · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
TRAINING FOR ACADEMIC ONCOLOGY/HEMATOLOGYT32CA009666 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michael Davies, Courtney DiNardo · 1994 to 2026
$9.8M
Neuromodulation as a Treatment for Chemotherapy-Induced Peripheral NeuropathyK01AT008485 · NCCIH · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI PRINSLOO, SARAH · 2014 to 2018
$647k
Biobehavioral Effects of Qigong During Treatment for Rectal CancerR21CA129201 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2008 to 2010
$500k
NCCIH NIH HHS K01 AT008485NCI NIH HHS P30 CA016672NCI NIH HHS R21 CA129201NCI NIH HHS T32 CA009666
6 · The paper itself

Abstract

objectivesSleep disturbances and fatigue are common in prostate cancer patients undergoing radiotherapy. Prior research suggests mind-body techniques may improve these outcomes. We conducted a randomized controlled trial of qigong/tai chi (QGTC) in men with prostate cancer undergoing radiotherapy.

methodsMen with prostate cancer starting definitive radiation were randomized to 1 of 3 groups: (1) QGTC; (2) light exercise (LE); or (3) waiting list control. Sleep disturbances (Pittsburgh Sleep Quality Index) and fatigue (Brief Fatigue Inventory) were assessed at baseline, midway through radiotherapy (T2), during the last week of radiotherapy (T3), and at 1 (T4) and 3 months (T5) after the end of radiotherapy. Patients in the QGTC and LE groups attended three 40-minute classes per week throughout radiotherapy.

resultsNinety patients were randomized to the 3 groups (QGTC = 26; LE = 26; waiting list control = 24). The QGTC group reported longer sleep duration midway through radiotherapy (QGTC = 7.01 h; LE = 6.42; WL = 6.50; P = .05), but this difference did not persist over time. There were no group differences in other domains of sleep or fatigue. Exploratory analyses conducted to examine the effect of health-related quality of life (Expanded Prostate Cancer Index Composite and American Urological Association Symptom score) on sleep and fatigue showed significant correlations across multiple domains.

conclusionsQigong/tai chi during radiation for prostate cancer resulted in superior sleep duration midway through radiation, but this effect was not durable, and there were no differences in other domains of sleep or fatigue. Exploratory analysis demonstrated that both sleep and fatigue were highly correlated with prostate cancer-related physical symptoms. Future mind-body intervention studies should incorporate multimodal therapy focused on improving physical symptoms in this population.

Indexed as

ExerciseQigongQuality of LifeTai JiWaiting ListsAgedFatigueHumansMaleMiddle AgedOutcome Assessment, Health CareProstatic NeoplasmsSleepSleep Wake DisordersTexasfatigueoncologyprostate cancerqigongsleeptai chi

Identifiers

PMID27548839
PMCPMC5378667
OpenAlexW2507904386

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.