Evidence map›Paper›PMID 27547982›Full record

ArticleACS chemical biology2016

Dual Readout BRET/FRET Sensors for Measuring Intracellular Zinc.

Stijn J A Aper, Pieterjan Dierickx, Maarten Merkx

Abstract read
In one paragraph

Article in ACS chemical biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Redesign of Calmodulin for Genetically Encoded ZnChemical & biomedical imaging · 2026
    Article
  2. Article
  3. Zinc in eye health, retinal biology and disease.Progress in retinal and eye research · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Ratiometric Detection of ZnChemistry (Basel, Switzerland) · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Tools and techniques for illuminating the cell biology of zinc.Biochimica et biophysica acta. Molecular cell research · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stijn J A AperLaboratory of Chemical Biology and Institute for Complex Molecular Systems (ICMS), Department of Biomedical Engineering, Eindhoven University of Technology , P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Pieterjan DierickxHubrecht Institute-KNAW and University Medical Center Utrecht , Utrecht, The Netherlands.
Maarten MerkxLaboratory of Chemical Biology and Institute for Complex Molecular Systems (ICMS), Department of Biomedical Engineering, Eindhoven University of Technology , P.O. Box 513, 5600 MB Eindhoven, The Netherlands.

Funding

European Research Council 280255
6 · The paper itself

Abstract

Genetically encoded FRET-based sensor proteins have significantly contributed to our current understanding of the intracellular functions of Zn

Indexed as

CatalysisFluorescence Resonance Energy TransferHomeostasisLuminescent MeasurementsSubcellular FractionsZincZinc

Identifiers

PMID27547982
PMCPMC5080634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.