ReviewInternational wound journal2016
A solution for complex wounds: the evidence for negative pressure wound therapy with instillation.
Review in International wound journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Vacuum-assisted closure versus conventional dressing in necrotizing fasciitis: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Outcomes of vacuum-assisted closure therapy (VAC) in patients with Fournier's gangrene: a retrospective cohort study.Irish journal of medical science · 2026Article
- Comparison between vacuum sealing drainage (VSD) and conventional dressing for fournier's gangrene: a single-centre retrospective study.BMC surgery · 2025Article
- Efficacy of hyperbaric oxygen therapy combine with negative pressure wound therapy in chronic wound: A randomized controlled trial.JPRAS open · 2025Article
- Clinical Significance of Vacuum assisted Closure in Management of Infected Wound: An Observational, Comparative Study.Journal of orthopaedic case reports · 2025Article
- Evolving Role of Negative Pressure Wound Therapy with Instillation and Dwell Time (NPWTi-d-) in Management of Trauma and Orthopaedic Wounds: Mechanism, Applications and Future Perspectives.Indian journal of orthopaedics · 2023Review
- Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds.International wound journal · 2022Review
- Article
- Treatment With Novel Foam Dressing of NPWTi-D for Postoperative Necrosis Complicated by Critical Limb Ischemia.Eplasty · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an adjunctive therapy that can be used in the management of complex wounds with infection. NPWTi-d incorporates the intermittent instillation of a topical solution to the wound in a programmed manner. Unlike standard negative pressure wound therapy, NPWTi-d delivers topical wound solutions directly to the wound, allows the solution to dwell over the wound bed, and removes the solution during the negative pressure phase. The authors review the evidence for using NPWTi-d and the role it may potentially play in helping to reduce hospital stay, number of debridement operations and cost.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.