ArticlePapillomavirus research (Amsterdam, Netherlands)2015
An analysis of HPV infection incidence and clearance by genotype and age in men: The HPV Infection in Men (HIM) Study.
Article in Papillomavirus research (Amsterdam, Netherlands), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis.The Lancet. Global health · 2023Pooled it
- Directionality of Genital Human Papillomavirus Infection Transmission Within Heterosexual Couples: A Systematic Review and Meta-analysis.The Journal of infectious diseases · 2020Pooled it
- Estimating incidence rates of grouped HPV types: A systematic review and comparison of the impact of different epidemiological assumptions.Papillomavirus research (Amsterdam, Netherlands) · 2019Pooled it
- High-Risk HPV in Men: A Hidden Threat to Public Health?Reviews in medical virology · 2026Review
- The relationship between human papillomavirus genotype distribution and age and the association with high-grade squamous intraepithelial lesions of the cervix or cervical cancer in Jilin Province, China.Virology journal · 2025Article
- Article
- Persistence and clearance of oral human papillomavirus among a multi-national cohort of men.Nature communications · 2025Article
- Detection of Human Papillomavirus in Urogenital Swabs from Male Patients in Northern Serbia.Pathogens (Basel, Switzerland) · 2025Article
- Natural history of HPV-16 E6 serology among cancer-free men in a multicenter longitudinal cohort study.Journal of the National Cancer Institute · 2025Article
- Article
- Health impact and cost-effectiveness analysis of gender-neutral versus female-only 9-valent human papillomavirus vaccination in Taiwan.PloS one · 2025Article
- Oral human papillomavirus (HPV) prevalence and genotyping among healthy adult populations in the United States and Europe: results from the PROGRESS (PRevalence of Oral hpv infection, a Global aSSessment) study.EClinicalMedicine · 2025Article
- High burden of human papillomavirus infection among men in Guangzhou, South China: Implications for HPV vaccination strategies.Human vaccines & immunotherapeutics · 2024Observational
- Article
- Prospective Longitudinal Study of Dynamics of Human Papillomavirus 6 and 11 Infection in Anogenital Hairs and Eyebrows of Male Patients with Anogenital Warts and Age-Matched Controls.Microorganisms · 2024Article
- Health impact and cost-effectiveness of implementing gender-neutral vaccination with the 9-valent HPV vaccine in Hong Kong.Human vaccines & immunotherapeutics · 2023Article
- Effectiveness, immunogenicity, and safety of the quadrivalent HPV vaccine in women and men aged 27-45 years.Human vaccines & immunotherapeutics · 2022Article
- Prevalence and Genotype Distribution of Human Papillomavirus Among Attendees at a Sexually Transmitted Diseases Clinic in Urban Tianjin, China.International journal of general medicine · 2021Article
- Prevalence, Incidence, and Clearance of Human Papillomavirus Types Covered by Current Vaccines in Men With Human Immunodeficiency Virus in the SUN Study.The Journal of infectious diseases · 2020Article
- Untangling the dynamics of persistence and colonization in microbial communities.The ISME journal · 2019Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectivesGenital HPV infection in men causes benign and cancerous lesions, the incidence of which differs by age. The goal of this work was to comprehensively evaluate incidence and clearance of individual HPV genotypes among men by age group.
methodsHIV-negative men ages 18-70 with no history of anogenital cancer were recruited for the
results4085 men were followed for a median of 48.6 months (range: 0.3-94.0). Significantly lower HPV incidence rates were observed among the oldest age group (55-70 years) for grouped high-risk (incidence rate ratio [IRR]=0.71), HPV16 (IRR=0.54), grouped low-risk (IRR=0.74), and HPV6 (IRR=0.57) infections compared to men ages 18-24. However, incidence of the grouped 9-valent HPV vaccine types remained constant across the lifespan. Likelihood of HPV6 and HPV16 clearance remained constant until age 54, then increased significantly for men ages 55-70 (adjusted hazard ratio [AHR]=1.92 and 1.65, respectively).
conclusionsMen remain susceptible to HPV infections throughout their lifespan, highlighting the need for prevention efforts with long-lasting duration.
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