ArticleCurrent clinical microbiology reports2016
Genetic Susceptibility to Fungal Infections: What is in the Genes?
Article in Current clinical microbiology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pharmacist involvement in antifungal stewardship programs: a systematic review of clinical, utilization, and economic outcomes.International journal of clinical pharmacy · 2026Pooled it
- Host genetic susceptibility to mycetoma.PLoS neglected tropical diseases · 2020Pooled it
- Climate Change Impacts on Environmental Fungi: Human Health and Fungal Disease.Current topics in microbiology and immunology · 2025Review
- Drivers of diversification in fungal pathogen populations.PLoS pathogens · 2024Review
- A Fun-Guide to Innate Immune Responses to Fungal Infections.Journal of fungi (Basel, Switzerland) · 2022Review
- Recipient and donor PTX3 rs2305619 polymorphisms increase the susceptibility to invasive fungal disease following haploidentical stem cell transplantation: a prospective study.BMC infectious diseases · 2022Article
- Pathogenesis of Respiratory Viral and Fungal Coinfections.Clinical microbiology reviews · 2022Review
- Host, pathogenic fungi and the microbiome: A genetic triangle in infection.Frontiers in immunology · 2022Article
- Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease.Open forum infectious diseases · 2021Review
- Challenges and Opportunities in Understanding Genetics of Fungal Diseases: Towards a Functional Genomics Approach.Infection and immunity · 2021Review
- Genetic Susceptibility to Fungal Infections and Links to Human Ancestry.Frontiers in genetics · 2021Review
- Structural and Bioactivity Characterization of Filipin Derivatives from EngineeredAntibiotics (Basel, Switzerland) · 2020Article
- Polymorphisms within theInfection and immunity · 2020Article
- Dectin-1 rs3901533 and rs7309123 Polymorphisms Increase Susceptibility to Pulmonary Invasive Fungal Disease in Patients with Acute Myeloid Leukemia from a Chinese Han Population.Current medical science · 2019Article
- How Environmental Fungi Cause a Range of Clinical Outcomes in Susceptible Hosts.Journal of molecular biology · 2019Review
- Invasive Fungal Infection.Deutsches Arzteblatt international · 2019Review
- Searching for Bacteria in Neural Tissue From Amyotrophic Lateral Sclerosis.Frontiers in neuroscience · 2019Article
- A case of invasive pulmonary aspergillosis during treatment for acute exacerbation of interstitial lung disease.Infectious disease reports · 2018Article
- Acidic Mammalian Chitinase Negatively Affects Immune Responses during Acute and Chronic Aspergillus fumigatus Exposure.Infection and immunity · 2018Article
- New Horizons in Antifungal Therapy.Journal of fungi (Basel, Switzerland) · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The development of severe fungal infections has long been associated with traditional risk factors such as profound immunosuppression, yet it remains challenging to understand why under similar conditions only some patients will develop these infections while others will not. Recent studies have demonstrated the importance of host genetic variation in influencing the severity and susceptibility to invasive fungal infections (IFIs). In this review, we examine selected primary immunodeficiencies characterized by their vulnerability to a narrow range of fungal pathogens, and then focus on recently identified genetic polymorphisms associated with an increased susceptibility to IFIs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.