Evidence map›Paper›PMID 27547681›Full record

ArticleSpringerPlus2016

Which is the best intrauterine insemination timing choice following exogenous hCG administration during ovulation induction by using clomiphene citrate treatment? A retrospective study.

Omer Hamid Yumusak, Serkan Kahyaoglu, Meryem Kuru Pekcan, Esra Isci, Şebnem Ozyer, Mahmut Nedim Cicek, Yasemin Tasci, Salim Erkaya

Open access · diamondAbstract read
In one paragraph

Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Omer Hamid YumusakDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Serkan KahyaogluDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Meryem Kuru PekcanDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Esra IsciDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Şebnem OzyerDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Mahmut Nedim CicekDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Yasemin TasciDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Salim ErkayaDepartment of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the impact of intrauterine insemination timing performed 24 or 36 h later following ovulation trigger on clinical pregnancy rate during ovulation induction with clomiphene citrate among infertile women was the objective of this study.

methodsThe medical records of 280 infertile patients who have underwent ovulation induction by using clomiphene citrate have been evaluated and cycle outcomes of the patients have been investigated specifically based on the timing of intrauterine insemination during the treatment cycle.

resultsThe clinical pregnancy rate of the study group based on the timing of intrauterine insemination (24 vs. 36 h following hCG trigger) was found to be similar regardless of infertility type. The cycle day of which hCG trigger has been performed was found to be significantly longer for patients who have achieved clinical pregnancy than patients who have not got pregnant following the treatment cycle. Dominant follicle diameter has not been found to affect clinical pregnancy rate during treatment cycles with clomiphene citrate.

conclusionsIn this study, intrauterine insemination timing did not affect the cycle outcomes whether the procedure has been performed 24 or 36 h later following ovulation trigger with exogenous hCG utilization. The longer period of treatment cycle during ovulation induction with clomiphene citrate resulted with higher clinical pregnancy rate. Intrauterine insemination can be done successfully at either 24 or 36 h after hCG in clomiphene citrate stimulated cycles. This will allow more flexibility and convenience for both physicians and patients, especially during weekends.

Indexed as

Clinical pregnancyClomiphene citrateInfertilityIntrauterine insemination

Identifiers

PMID27547681
PMCPMC4978662
OpenAlexW2510469783

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.