ArticleSpringerPlus2016
Health-related quality of life after deep vein thrombosis.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Patient-Reported Outcomes in Venous Thromboembolism: A Systematic Review of the Literature, Current Challenges, and Ways Forward.Journal of the American Heart Association · 2023Pooled it
- Patient values and preferences regarding VTE disease: a systematic review to inform American Society of Hematology guidelines.Blood advances · 2020Pooled it
- Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2019Pooled it
- Item generation for a new disease-specific health-related quality of life questionnaire in patients with deep vein thrombosis: an international multicenter study.Research and practice in thrombosis and haemostasis · 2026Article
- Hemostatic and Inflammatory Biomarkers are Associated with Functional Limitations after Venous Thromboembolism: A Prospective Cohort Study.Seminars in thrombosis and hemostasis · 2025Article
- Delayed diagnosis and treatment of deep vein thrombosis - an underrecognized factor for its related outcomes?Thrombosis journal · 2025Article
- Article
- Health-related quality of life after first venous thromboembolism in individuals aged 70 years and older.Research and practice in thrombosis and haemostasis · 2023Article
- Using early health economic modeling to inform medical innovation development: a soft robotic sock in poststroke patients in Singapore.International journal of technology assessment in health care · 2023Article
- Single-center experience with the ClotTriever BOLD catheter for deep vein thrombosis percutaneous mechanical thrombectomy of the lower extremity.Frontiers in surgery · 2023Article
- Association between VTE and antibiotic prophylaxis guideline compliance and patient-reported outcomes after total hip and knee arthroplasty: an observational study.Journal of patient-reported outcomes · 2022Article
- The venous thrombosis registry in Østfold Hospital (TROLL registry) - design and cohort description.Research and practice in thrombosis and haemostasis · 2022Article
- Quality of Life Status and Influencing Factors Among Patients with Deep Vein Thrombosis.Patient preference and adherence · 2022Article
- Article
- Practice patterns of VTE chemoprophylaxis after discharge following hepatic and pancreatic resections for cancer: A survey of hepatopancreatobiliary surgeons.Journal of thrombosis and thrombolysis · 2019Article
- Cost-Effectiveness of Betrixaban Compared with Enoxaparin for Venous Thromboembolism Prophylaxis in Nonsurgical Patients with Acute Medical Illness in the United States.PharmacoEconomics · 2019Article
- Venous thromboembolism in patients with cancer undergoing surgical exploration.Journal of thrombosis and thrombolysis · 2019Article
- Prevention and treatment of the post-thrombotic syndrome.Research and practice in thrombosis and haemostasis · 2018Article
- Article
- Deep Vein Thrombosis Interventions in Cancer Patients.Seminars in interventional radiology · 2017Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHealth-related quality of life (HRQoL) is known to be impaired in patients who develop post-thrombotic syndrome (PTS) following deep vein thrombosis (DVT). However, there is limited knowledge of the long-term HRQoL after DVT compared to controls without DVT. The objectives of this study were to evaluate long-term HRQoL following DVT and to compare that with age and sex matched control group and to population norms as well as to investigate possible predictors for reduced HRQoL.
methodsHRQoL was evaluated in 254 patients with confirmed DVT using the generic EQ-5D and the diseases specific VEINES-QOL/Sym questionnaire, whereas PTS was assessed by the Villalta scale. Patients were asked to give the EQ-5D questionnaire to two friends of same age- (±5 years) and sex (buddy controls).
resultsPatients scored significantly lower on all dimensions of EQ-5D compared to controls. EQ-5D index value was lower in patients compared with buddy controls; mean 0.79 (SD 0.17; IQR 0.72-1.00) versus 0.9 (SD 0.12; IQR 0.80-1.00), p < 0.001. EQ-5D index value was also significantly lower than age- and sex-adjusted population norms (p < 0.001). PTS and obesity (BMI >30/m(2)) were significantly associated with impaired HRQoL assessed by EQ-5D index value (odds ratio [OR] 11.0: 95 % confidence interval [CI] 4.6-29.7; and 2.3: 95 % CI 1.1-4.8, respectively) and VEINES-QOL (OR 28.2: 95 % CI 10.6-75.0; and OR 4.1: 95 % CI 1.7-9.7, respectively).
conclusionLong-term HRQoL was significantly impaired in DVT patients compared with buddy controls and population norms. PTS and obesity were independently associated with impaired HRQoL.
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