Evidence map›Paper›PMID 27547503›Full record

ArticleBrain and behavior2016

Brain potentials predict substance abuse treatment completion in a prison sample.

Brandi C Fink, Vaughn R Steele, Michael J Maurer, Samantha J Fede, Vince D Calhoun, Kent A Kiehl

Abstract read
In one paragraph

Article in Brain and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brandi C FinkDepartment of Psychiatry and Behavioral Sciences Clinical and Translational Science Center The University of New Mexico Albuquerque New Mexico.
Vaughn R SteeleIntramural Research Program Neuroimaging Research Branch National Institute of Drug Abuse National Institutes of Health Baltimore Maryland; The Mind Research Network and Lovelace Biomedical and Environmental Research Institute Albuquerque New Mexico; Department of Psychology The University of New Mexico Albuquerque New Mexico.
Michael J MaurerThe Mind Research Network and Lovelace Biomedical and Environmental Research Institute Albuquerque New Mexico; Department of Psychology The University of New Mexico Albuquerque New Mexico.
Samantha J FedeThe Mind Research Network and Lovelace Biomedical and Environmental Research Institute Albuquerque New Mexico; Department of Psychology The University of New Mexico Albuquerque New Mexico.
Vince D CalhounThe Mind Research Network and Lovelace Biomedical and Environmental Research Institute Albuquerque New Mexico; Department of Electrical and Computer Engineering The University of New Mexico Albuquerque New Mexico.
Kent A KiehlThe Mind Research Network and Lovelace Biomedical and Environmental Research Institute Albuquerque New Mexico; Department of Psychology The University of New Mexico Albuquerque New Mexico.

Funding

UNM HSC Clinical and Translational Science CenterUL1TR001449 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J, PANDHI, NANCY · 2015 to 2024
$36.9M
University of New Mexico Center for Metals in Biology and Medicine - equipment supplementP20GM130422 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Priscilla Marie De La Cruz · 2020 to 2026
$20.4M
Transcranial Direct Current Stimulation for Treatment of Auditory Verbal HalluciP20GM103472 · NIGMS · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D · 2012 to 2017
$14.3M
University of New Mexico Clinical and Translational Science CenterKL2TR001448 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CANNON, JUDY LIN · 2015 to 2024
$3.5M
Neurocognitive Changes Associated with Behavioral Treatment in Cocaine AbusersR01DA020870 · NIDA · THE MIND RESEARCH NETWORK · PI KIEHL, KENT A · 2005 to 2009
$3.0M
Over-Arousal as a Mechanism between Alcohol and Intimate Partner ViolenceR21AA022367 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CLAUS, ERIC D, FINK, BRANDI C · 2015 to 2016
$425k
NCATS NIH HHS KL2 TR001448NCATS NIH HHS UL1 TR001449NIAAA NIH HHS R21 AA022367NIDA NIH HHS R01 DA020870NIGMS NIH HHS P20 GM103472NIGMS NIH HHS P20 GM130422
6 · The paper itself

Abstract

introductionNational estimates suggest that up to 80% of prison inmates meet diagnostic criteria for a substance use disorder. Because more substance abuse treatment while incarcerated is associated with better post-release outcomes, including a reduced risk of accidental overdose death, the stakes are high in developing novel predictors of substance abuse treatment completion in inmate populations.

methodsUsing electroencephalography (EEG), this study investigated stimulus-locked ERP components elicited by distractor stimuli in three tasks (VO-Distinct, VO-Repeated, Go/NoGo) as a predictor of treatment discontinuation in a sample of male and female prison inmates. We predicted that those who discontinued treatment early would exhibit a less positive P3a amplitude elicited by distractor stimuli.

resultsOur predictions regarding ERP components were partially supported. Those who discontinued treatment early exhibited a less positive P3a amplitude and a less positive PC4 in the VO-D task. In the VO-R task, however, those who discontinued treatment early exhibited a more negative N200 amplitude rather than the hypothesized less positive P3a amplitude. The discontinuation group also displayed less positive PC4 amplitude. Surprisingly, there were no time-domain or principle component differences among the groups in the Go/NoGo task. Support Vector Machine (SVM) models of the three tasks accurately classified individuals who discontinued treatment with the best model accurately classifying 75% of inmates. PCA techniques were more sensitive in differentiating groups than the classic time-domain windowed approach.

conclusionsOur pattern of findings are consistent with the context-updating theory of P300 and may help identify subtypes of ultrahigh-risk substance abusers who need specialized treatment programs.

Indexed as

Patient CompliancePrisonersAdultElectroencephalographyEvent-Related Potentials, P300Evoked PotentialsFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePrincipal Component AnalysisPrognosisSubstance-Related DisordersSupport Vector MachineYoung AdultEvent‐related potentialspattern classifierprincipal component analysisprison inmatesubstance abuse treatmentsupport vector machine

Identifiers

PMID27547503
PMCPMC4893048

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.