ReviewArab journal of urology2016
The challenges in the diagnosis of detrusor underactivity in clinical practice: A mini-review.
Review in Arab journal of urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Autologous adipose-derived mesenchymal stem cell therapy reverses detrusor underactivity: open clinical trial.Stem cell research & therapy · 2023Trial
- Clinical utility of urinary microRNA (miR-1273g-3p) in male patients with detrusor underactivity.World journal of urology · 2026Article
- Clinical predictors of bladder outlet obstruction in men consulting for routine urological screening.International urology and nephrology · 2025Article
- Urodynamic evaluation of neurogenic bladder in patients with spinal cord injury within 6 months post-injury: a Retrospective Cross-Sectional Study.Spinal cord · 2025Article
- Diagnoses and Treatment Recommendations-Interrater Reliability of Uroflowmetry in People with Multiple Sclerosis.Biomedicines · 2024Article
- Do urodynamics predict urinary retention after sling placement in the complex patient: the value of reproducing symptoms on urodynamics.International urogynecology journal · 2021Article
- The correlation between diffusion tensor imaging of the sacral cord and bladder contractility in people with tetraplegia.Spinal cord · 2020Article
- The Prevalence of Detrusor Underactivity and its Symptoms Co-relation with Urodynamic Study Findings in Patients with Lower Urinary Tract Symptoms.Research and reports in urology · 2020Article
- Urodynamic factors associated with the large capacity bladder and incomplete emptying after prolapse repair (2009-2015).Neurourology and urodynamics · 2019Article
- Observational
- GreenLight laser photoselective vaporization of the prostate for treatment of benign prostate hyperplasia/lower urinary tract symptoms in patients with different post-void residual urine.Lasers in medical science · 2017Article
- Assessment of noninvasive predictors of bladder detrusor underactivity in BPH/LUTs patients.International urology and nephrology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo review the current definitions, terminology, epidemiology and aetiology of detrusor underactivity (DU), with specific attention to the diagnostic criteria in use. In addition, we address the relation and the overlap between DU and bladder outlet obstruction (BOO). In this mini-review, we hope to help identify DU patients and facilitate structured clinical evaluation and research.
methodsWe searched the English literature using ScienceDirect and PubMed for relevant articles. We used the following terms: 'detrusor underactivity', 'underactive bladder', 'post voiding residual', 'post micturition residual', 'acontractile bladder', 'detrusor failure', and 'detrusor areflexia'.
resultDU is one of the most common conditions causing lower urinary tract symptoms (LUTS). Unfortunately, it is also the most poorly understood bladder dysfunction with scant research. To our knowledge there is no clear definition and no non-invasive method to characterise this important clinical condition. DU may result from the normal ageing process; however, it has multiple aetiologies including neurogenic and myogenic dysfunction. In many cases the symptoms of DU are similar to those of BOO and it usually requires invasive urodynamic study (UDS) for diagnosis to differentiate the two diagnoses. A number of diagnostic tests may be used including: UDS testing, the Schafer pressure/flow nomogram, linear passive urethral resistance relation, Watts factor, and the bladder contractility index. Of these, UDS testing is the most practical as it determines both the maximum urinary flow rate and the pressure exerted by the detrusor muscle relative to the maximal flow of urine, allowing for precise characterisation of detrusor function.
conclusionCurrently, the diagnosis of DU is based on invasive urodynamic parameters as defined by the International Continence Society in 2002. There is no consensus for the definition of DU prior to 2002. As there is significant overlap between the symptoms of DU and BOO, it is difficult to diagnose DU clinically.
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