ArticleEcology and evolution2016
Life history evolution and cellular mechanisms associated with increased size in high-altitude Drosophila.
Article in Ecology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Shared candidate genes associated with variation in egg size in cold-adapted and artificially selected Drosophila melanogaster.Developmental biology · 2026Article
- Rapid wing size evolution in African fig flies (Zaprionus indianus) following temperate colonization.Evolution; international journal of organic evolution · 2025Article
- The Precision and Power of Population Branch Statistics in Identifying the Genomic Signatures of Local Adaptation.Genome biology and evolution · 2025Article
- The potential of inversions to accumulate balanced sexual antagonism is supported by simulations andeLife · 2025Article
- No degradation of temperature-mediated phenotypic plasticity inmicroPublication biology · 2025Article
- Genomic Diversity Illuminates the Environmental Adaptation of Drosophila suzukii.Genome biology and evolution · 2024Article
- Developmental noise and phenotypic plasticity are correlated inEvolution letters · 2024Article
- Evolution of compound eye morphology underlies differences in vision between closely related Drosophila species.BMC biology · 2024Article
- Female lizards (Ecology and evolution · 2023Article
- Hybrid breakdown in male reproduction between recently diverged Drosophila melanogaster populations has a complex and variable genetic architecture.Evolution; international journal of organic evolution · 2023Article
- Long-term evolution of quantitative traits in the Drosophila melanogaster species subgroup.Genetica · 2022Article
- The evolution of larger size in high-altitude Drosophila melanogaster has a variable genetic architecture.G3 (Bethesda, Md.) · 2022Article
- Drosophila Sirtuin 6 mediates developmental diet-dependent programming of adult physiology and survival.Aging cell · 2022Article
- Review
- Evolution of Ovipositor Length in Drosophila suzukii Is Driven by Enhanced Cell Size Expansion and Anisotropic Tissue Reorganization.Current biology : CB · 2019Article
- Genetic variation in PTPN1 contributes to metabolic adaptation to high-altitude hypoxia in Tibetan migratory locusts.Nature communications · 2018Article
- Effect of Larval Nutrition on Maternal mRNA Contribution to theG3 (Bethesda, Md.) · 2018Article
- Seasonal variations in body melanism and size of the wolf spiderEcology and evolution · 2018Article
- Mid-day siesta in natural populations of D. melanogaster from Africa exhibits an altitudinal cline and is regulated by splicing of a thermosensitive intron in the period clock gene.BMC evolutionary biology · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Understanding the physiological and genetic basis of growth and body size variation has wide-ranging implications, from cancer and metabolic disease to the genetics of complex traits. We examined the evolution of body and wing size in high-altitude Drosophila melanogaster from Ethiopia, flies with larger size than any previously known population. Specifically, we sought to identify life history characteristics and cellular mechanisms that may have facilitated size evolution. We found that the large-bodied Ethiopian flies laid significantly fewer but larger eggs relative to lowland, smaller-bodied Zambian flies. The highland flies were found to achieve larger size in a similar developmental period, potentially aided by a reproductive strategy favoring greater provisioning of fewer offspring. At the cellular level, cell proliferation was a strong contributor to wing size evolution, but both thorax and wing size increases involved important changes in cell size. Nuclear size measurements were consistent with elevated somatic ploidy as an important mechanism of body size evolution. We discuss the significance of these results for the genetic basis of evolutionary changes in body and wing size in Ethiopian D. melanogaster.
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