Chronic Rhinosinusitis and Irritable Bowel Syndrome: A Case Report.

Mikhail Kogan, Carlos Cuellar Castillo, Melissa S Barber

Open access · greenAbstract readCase Reports

In one paragraph

Article in Integrative medicine (Encinitas, Calif.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed, 1 pooled it

0.8field-weighted citation impact, top 25% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

CARE-radiology statement explanation and elaboration: reporting guideline for radiological case reports.BMJ evidence-based medicine · 2024
Guideline

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mikhail KoganMikhail Kogan, md , is medical director at George Washington University, G. W. Center for Integrative Medicine, in Washington, DC. Carlos Cuellar Castillo, ms , is a graduate of the physiology master of science program and complementary and alternative medicine at Georgetown University, in Washington, DC. Melissa S. Barber, ms , is at Helfgott Research Institute, National University of Natural Medicine, in Portland, Oregon.

Carlos Cuellar CastilloMikhail Kogan, md , is medical director at George Washington University, G. W. Center for Integrative Medicine, in Washington, DC. Carlos Cuellar Castillo, ms , is a graduate of the physiology master of science program and complementary and alternative medicine at Georgetown University, in Washington, DC. Melissa S. Barber, ms , is at Helfgott Research Institute, National University of Natural Medicine, in Portland, Oregon.

Melissa S BarberMikhail Kogan, md , is medical director at George Washington University, G. W. Center for Integrative Medicine, in Washington, DC. Carlos Cuellar Castillo, ms , is a graduate of the physiology master of science program and complementary and alternative medicine at Georgetown University, in Washington, DC. Melissa S. Barber, ms , is at Helfgott Research Institute, National University of Natural Medicine, in Portland, Oregon.

Georgetown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic rhinosinusitis (CRS) and irritable bowel syndrome (IBS) can be comorbidities that are difficult to treat. In this patient, an evidence-informed treatment pathway guided by laboratory biomarkers was used to address both conditions. CASE PRESENTATION: A 69-y-old female patient presented with a 50-y history of sinusitis that was worse in the winter, postnasal drip, frequent sore throats, gastrointestinal complaints, headaches, and yeast infections. Two sinus surgeries (in years 2000 and 2002) and multiple courses of antibiotics had not resolved her sinus symptoms. In addition to CRS and IBS, this patient was noted to have intestinal overgrowth of Candida albicans, multiple food sensitivities, and leaky gut syndrome.

conclusionAntifungal medication and dietary changes in the course of 8 mo resulted in the resolution of her CRS and IBS.

Identifiers

PMID27547167

PMCPMC4982648

OpenAlexW2518334919

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.