Evidence map›Paper›PMID 27547159›Full record

ArticleJournal of nanoscience and nanotechnology2016

Silicon Dioxide Impedes Antiviral Response and Causes Genotoxic Insult During Calicivirus Replication.

Sudhakar S Agnihothram, Sheryl Anne Vermudez, Lisa Mullis, Todd A Townsend, Mugimane G Manjanatha, Marli P Azevedo

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanoscience and nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sudhakar S AgnihothramUnited States Food and Drug Administration, National Center for Toxicological Research (NCTR), Division of Microbiology, Honolulu, Hawaii, 96816, USA.
Sheryl Anne VermudezUnited States Food and Drug Administration, National Center for Toxicological Research (NCTR), Division of Microbiology, Honolulu, Hawaii, 96816, USA; Chaminade University of Honolulu, Honolulu, Hawaii, 96816, USA.
Lisa MullisUnited States Food and Drug Administration, National Center for Toxicological Research (NCTR), Division of Microbiology, Honolulu, Hawaii, 96816, USA.
Todd A TownsendUnited States Food and Drug Administration, National Center for Toxicological Research (NCTR), Division of Genetic and Molecular Toxicology, Honolulu, Hawaii, 96816, USA.
Mugimane G ManjanathaUnited States Food and Drug Administration, National Center for Toxicological Research (NCTR), Division of Genetic and Molecular Toxicology, Honolulu, Hawaii, 96816, USA.
Marli P AzevedoUnited States Food and Drug Administration, National Center for Toxicological Research (NCTR), Division of Microbiology, Honolulu, Hawaii, 96816, USA.
National Center for Toxicological Research · USChaminade University of Honolulu · US

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
Intramural FDA HHS FD999999NIGMS NIH HHS P20 GM103466
6 · The paper itself

Abstract

Noroviruses (NoV) are the leading cause of nonbacterial gastroenteritis in humans, and replicate extensively in the human gastrointestinal (GI) tract. Silica (also known as silicon dioxide, SiO

Indexed as

Feline CalicivirusGenotoxicityMurine NorovirusProinflammatory ResponseSilica

Identifiers

PMID27547159
PMCPMC4986603
OpenAlexW2413786821

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.