ArticleBMC ear, nose, and throat disorders2016
Exogenous lipid pneumonia related to long-term use of Vicks VapoRub® by an adult patient: a case report.
Article in BMC ear, nose, and throat disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Acute exogenous lipoid pneumonia leading to severe ARDS: a case report.BMC pulmonary medicine · 2025Article
- There's the Rub: a narrative review of the benefits and complications associated with Vicks VapoRub use.PeerJ · 2025Review
- Mycobacterium infection secondary to exogenous lipoid pneumonia caused by nasal drops: a case report and literature review.BMC pulmonary medicine · 2023Review
- Appropriate use of essential oils and their components in the management of upper respiratory tract symptoms in patients with COVID-19.Journal of herbal medicine · 2021Review
- A case report of exogenous lipoid pneumonia associated with avocado/soybean unsaponifiables.BMC pulmonary medicine · 2019Article
- Exogenous Lipoid Pneumonia due to Chronic Inhalation of Oily Product Used as a Lubricant of Tracheotomy Cannula.The Eurasian journal of medicine · 2018Article
- Nasal application of petrolatum ointment - A silent cause of exogenous lipoid pneumonia: Successfully treated with prednisolone.Respiratory medicine case reports · 2017Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUse of petroleum-based over the counter remedies such as Vicks VapoRub to alleviate symptoms of rhinitis is common and can be effective, but carries under-appreciated risks of adverse side effects. In this case report we highlight Exogenous Lipoid Pneumonia (ELP), an uncommon condition that results from accumulation of exogenous lipids in the alveoli, as an adverse side effect of long-term Vicks VapoRub use. CASE PRESENTATION: We present the case of an 85-year-old female patient with ELP apparently due to continuous application of Vicks VapoRub® to her nostrils to alleviate chronic rhinitis. She was diagnosed incidentally via chest radiograph and computed tomography (CT) scan done as follow up to finding elevated C-reactive Protein during a routine exam. The CT scan revealed a pulmonary consolidation in the lower lobe of the right lung with fat density combined with low density areas associated with focal ground-glass opacities. The patient was advised to discontinue use of petroleum-based products, and was prescribed intranasal corticosteroids for her rhinitis. Follow up 2 years later showed that the lipid consolidation had diminished in size by approximately 10 %.
conclusionPhysicians must be aware that ELP can develop as a result of long-term application of petroleum-based oils and ointments to the nose and discourage such use of these products. Patients who have used petroleum-based products in this way should be screened for ELP. CT scan is the best imaging modality for establishing the diagnosis. The treatment of this condition is not well defined, but, as shown in this case, the size of the lipid mass can decrease after use of petroleum based substances is discontinued.
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