ArticleIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
Noncontact Elastic Wave Imaging Optical Coherence Elastography for Evaluating Changes in Corneal Elasticity Due to Crosslinking.
Article in IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32 citing papers in PubMed, 49 citations in OpenAlex.
- Biomechanical assessments of high-fluence corneal cross-linking with supplemental oxygen using optical coherence elastography inJournal of biomedical optics · 2026Article
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- CorvisThe British journal of ophthalmology · 2026Article
- Clinical multimodal Brillouin microscopy-optical coherence elastography system for lens biomechanics.Journal of biomedical optics · 2025Article
- Ultra-fast line-field swept source scanning optical coherence elastography.Biomedical optics express · 2025Article
- Article
- Assessing corneal cross-linking with reverberant 3D optical coherence elastography.Journal of biomedical optics · 2022Article
- Multimodal Heartbeat and Compression Optical Coherence Elastography for Mapping Corneal Biomechanics.Frontiers in medicine · 2022Article
- Wave-based optical coherence elastography: The 10-year perspective.Progress in biomedical engineering (Bristol, England) · 2022Article
- Quantitative compressive optical coherence elastography using structural OCT imaging and optical palpation to measure soft contact lens mechanical properties.Biomedical optics express · 2021Article
- 2-D Ultrasonic Array-Based Optical Coherence Elastography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- Heartbeat OCE: corneal biomechanical response to simulated heartbeat pulsation measured by optical coherence elastography.Journal of biomedical optics · 2020Article
- Clinical Corneal Optical Coherence Elastography Measurement Precision: Effect of Heartbeat and Respiration.Translational vision science & technology · 2020Article
- Multimodal quantitative optical elastography of the crystalline lens with optical coherence elastography and Brillouin microscopy.Biomedical optics express · 2020Article
- In vivo evaluation of corneal biomechanical properties by optical coherence elastography at different cross-linking irradiances.Journal of biomedical optics · 2019Article
- Simultaneously imaging and quantifyingAPL photonics · 2019Article
- Spatial resolution in dynamic optical coherence elastography.Journal of biomedical optics · 2019Article
- Assessment of the changes in corneal biomechanical properties after collagen cross-linking in patients with keratoconus.Journal of current ophthalmology · 2019Article
- Longitudinal elastic wave imaging using nanobomb optical coherence elastography.Optics letters · 2019Article
- Ultrasonic Microelastography to Assess Biomechanical Properties of the Cornea.IEEE transactions on bio-medical engineering · 2019Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
The mechanical properties of tissues can provide valuable information about tissue integrity and health and can assist in detecting and monitoring the progression of diseases such as keratoconus. Optical coherence elastography (OCE) is a rapidly emerging technique, which can assess localized mechanical contrast in tissues with micrometer spatial resolution. In this work we present a noncontact method of optical coherence elastography to evaluate the changes in the mechanical properties of the cornea after UV-induced collagen cross-linking. A focused air-pulse induced a low amplitude (μm scale) elastic wave, which then propagated radially and was imaged in three dimensions by a phase-stabilized swept source optical coherence tomography (PhS-SSOCT) system. The elastic wave velocity was translated to Young's modulus in agar phantoms of various concentrations. Additionally, the speed of the elastic wave significantly changed in porcine cornea before and after UV-induced corneal collagen cross-linking (CXL). Moreover, different layers of the cornea, such as the anterior stroma, posterior stroma, and inner region, could be discerned from the phase velocities of the elastic wave. Therefore, because of noncontact excitation and imaging, this method may be useful for
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.