Evidence map›Paper›PMID 27546836›Full record

ArticleJournal of neuroscience research2017

Protein kinase Cɛ activity regulates mGluR5 surface expression in the rat nucleus accumbens.

Marek Schwendt, M Foster Olive

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroscience research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Protein kinase C: perfectly balanced.Critical reviews in biochemistry and molecular biology · 2018
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marek SchwendtPsychology Department, University of Florida, Gainesville, Florida.
M Foster OlivePsychology Department, Arizona State University, Tempe, Arizona.
Arizona State University · USUniversity of Florida · US

Funding

Control of ethanol intake by mGluR5-PKCepsilon pathwayR01AA013852 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OLIVE, M. FOSTER · 2003 to 2013
$2.7M
Metabotropic Glutamate Receptor Signaling and Extinction LearningR01DA024355 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OLIVE, M. FOSTER · 2007 to 2011
$1.5M
Striatal RGS4 Interacts with mGluR5 Signaling in Relapse to Cocaine-seekingR21DA025846 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SCHWENDT, MAREK · 2010 to 2011
$400k
Optogenetic Targeting of mGluR5 Receptor SignalingR21DA037741 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI OLIVE, M. FOSTER · 2014 to 2015
$383k
NIAAA NIH HHS R01 AA013852NIDA NIH HHS R01 DA024355NIDA NIH HHS R21 DA025846NIDA NIH HHS R21 DA037741
6 · The paper itself

Abstract

Type 5 metabotropic glutamate receptors (mGluR5) activate protein kinase C (PKC) via coupling to G

Indexed as

AnimalsBiotinylationCalnexinDose-Response Relationship, DrugEnzyme ActivatorsEnzyme InhibitorsFatty Acids, MonounsaturatedGene Expression RegulationIn Vitro TechniquesMaleMethoxyhydroxyphenylglycolNucleus AccumbensPeptidesPhosphorylationProtein BiosynthesisProtein Kinase C-epsilon3,4-dihydroxyphenylglycol9-tetradecenoic acidCalnexinEnzyme ActivatorsEnzyme InhibitorsFatty Acids, MonounsaturatedMethoxyhydroxyphenylglycolPeptidesProtein Kinase C-epsilonReceptor, Metabotropic Glutamate 5Syntaxin 1acute brain slicesERK1/2membrane traffickingphosphorylationsurface biotinylationTat peptide

Identifiers

PMID27546836
PMCPMC5296288
OpenAlexW2514966569

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.