ArticleScientific reports2016
Optical coherence microscopy in 1700 nm spectral band for high-resolution label-free deep-tissue imaging.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed.
- Reflection matrix microscopy at 1.6 µm wavelength for label-free deep-tissue imaging.Biomedical optics express · 2026Article
- Broadband 2-µm fiber-laser supercontinuum for high-resolution optical coherence tomography.Biomedical optics express · 2026Article
- Simultaneous three-photon and optical coherence microscopy deep within an intact mouse brain.Npj imaging · 2026Article
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- Review of shortwave infrared imaging and spectroscopy in tissue [Invited].Biomedical optics express · 2025Review
- Compact femtosecond fiber laser tunable from 800 to 850 nm with pulse energy exceeding 5 nJ.Scientific reports · 2025Article
- Enhanced microvascular imaging through deep learning-driven OCTA reconstruction with squeeze-and-excitation block integration.Biomedical optics express · 2024Article
- Discontinuity third harmonic generation microscopy for label-free imaging and quantification of intraepidermal nerve fibers.Cell reports methods · 2024Article
- Closed-loop wavefront sensing and correction in the mouse brain with computed optical coherence microscopy.Biomedical optics express · 2021Article
- Capability of physically reasonable OCT-based differentiation between intact brain tissues, human brain gliomas of different WHO grades, and glioma model 101.8 from rats.Biomedical optics express · 2020Article
- Signal-to-background ratio and lateral resolution in deep tissue imaging by optical coherence microscopy in the 1700 nm spectral band.Scientific reports · 2019Article
- Review
- Noninvasive, in vivo rodent brain optical coherence tomography at 2.1 microns.Optics letters · 2019Article
- Detection of weak near-infrared optical imaging signals under ambient light by optical parametric amplification.Optics letters · 2019Article
- High-spatial-resolution deep tissue imaging with spectral-domain optical coherence microscopy in the 1700-nm spectral band.Journal of biomedical optics · 2019Article
- Computational analysis of six optical coherence tomography systems for vocal fold imaging: A comparison study.Lasers in surgery and medicine · 2019Article
- Article
- Deep brain optical coherence tomography angiography in mice: in vivo, noninvasive imaging of hippocampal formation.Scientific reports · 2018Article
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4 authors.
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Abstract
Optical coherence microscopy (OCM) is a label-free, high-resolution, three-dimensional (3D) imaging technique based on optical coherence tomography (OCT) and confocal microscopy. Here, we report that the 1700-nm spectral band has the great potential to improve the imaging depth in high-resolution OCM imaging of animal tissues. Recent studies to improve the imaging depth in OCT revealed that the 1700-nm spectral band is a promising choice for imaging turbid scattering tissues due to the low attenuation of light in the wavelength region. In this study, we developed high-resolution OCM by using a high-power supercontinuum source in the 1700-nm spectral band, and compared the attenuation of signal-to-noise ratio between the 1700-nm and 1300-nm OCM imaging of a mouse brain under the condition of the same sensitivity. The comparison clearly showed that the 1700-nm OCM provides larger imaging depth than the 1300-nm OCM. In this 1700-nm OCM, the lateral resolution of 1.3 μm and the axial resolution of 2.8 μm, when a refractive index was assumed to be 1.38, was achieved.
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