ReviewDeutsches Arzteblatt international2016
The Diagnosis and Treatment of Nail Disorders.
Review in Deutsches Arzteblatt international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 80 citations in OpenAlex.
- Interleukins decrease epithelial protein and gene expression by K14 + CD105+ equine hoof progenitor cells.Stem cell research & therapy · 2026Article
- Squamous Cell Carcinoma of the Nail Unit: A Comprehensive Review of Clinical Features, Diagnostic Workflow, Management Strategies and Therapeutic Options.Diagnostics (Basel, Switzerland) · 2025Review
- [Nail psoriasis-painful and yet undertreated : From pathogenesis to therapy].Dermatologie (Heidelberg, Germany) · 2025Article
- Dermoscopic Evaluation of Nail Changes in Patients with End-Stage Renal Disease on Regular Hemodialysis.Skin appendage disorders · 2025Article
- [Dermatomycoses: topical and systemic antifungal treatment].Dermatologie (Heidelberg, Germany) · 2024Review
- Dermoscopic Nail Disorders in School-Going Children.Cureus · 2023Article
- Classification of melanonychia, Beau's lines, and nail clubbing based on nail images and transfer learning techniques.PeerJ. Computer science · 2023Article
- Development and Validation of a Patient-Reported Outcome Measure for Fingernail and Toenail Conditions: The NAIL-Q.Clinical, cosmetic and investigational dermatology · 2023Article
- Comparative Ungual Drug Uptake Studies: Equine Hoof Membrane vs. Human Nail Plate.Pharmaceutics · 2022Article
- Article
- Deep Learning Assisted Diagnosis of Onychomycosis on Whole-Slide Images.Journal of fungi (Basel, Switzerland) · 2022Article
- [Unguis incarnatus-conservative or operative treatment? A practical treatment algorithm].Der Unfallchirurg · 2021Article
- Article
- Retronychia-an uncommon cause of chronic proximal nail fold inflammation.Wiener medizinische Wochenschrift (1946) · 2021Article
- Median nail dystrophy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020Article
- [Onychomycosis: Practical treatment strategies].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2018Review
- Subungual Nail Pigmentation and Malalignment of the Great Toe Nail in a Cancer Patient - A Diagnostic Challenge.Open access Macedonian journal of medical sciences · 2017Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNail disorders can arise at any age. About half of all nail disorders are of infectious origin, 15% are due to inflammatory or metabolic conditions, and 5% are due to malignancies and pigment disturbances. The differential diagnosis of nail disorders is often an area of uncertainty.
methodsThis review is based on publications and guidelines retrieved by a selective search in PubMed, including Cochrane reviews, meta-analyses, and AWMF guidelines.
resultsNail disorders are a common reason for derma - tologic consultation. They are assessed by clinical inspection, dermatoscopy, diagnostic imaging, microbiological (including mycological) testing, and histopathological examination. Some 10% of the overall population suffers from onychomycosis, with a point prevalence of around 15%. Bacterial infections of the nails are rarer than fungal colonization. High-risk groups for nail disorders include diabetics, dialysis patients, transplant recipients, and cancer patients. Malignant tumors of the nails are often not correctly diagnosed at first. For subungual melanoma, the mean time from the initial symptom to the correct diagnosis is approximately 2 years; this delay is partly responsible for the low 10-year survival rate of only 43%.
conclusionEvaluation of the nail organ is an important diagnostic instrument. Aside from onychomycosis, which is a common nail disorder, important differential diagnoses such as malignant diseases, drug side effects, and bacterial infections must be considered.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.