Evidence map›Paper›PMID 27544535›Full record

ArticleMycopathologia2016

In Vitro Activity of Melaleuca alternifolia (Tea Tree) in Its Free Oil and Nanoemulsion Formulations Against Pythium insidiosum.

Júlia de Souza Silveira Valente, Anelise de Oliveira da Silva Fonseca, Carolina Litchina Brasil, Lauren Sagave, Fernanda Cramer Flores, Cristiane de Bona da Silva, Luís Antônio Sangioni, Luciana Pötter, Janio Morais Santurio, Sônia de Avila Botton and 1 more

Abstract read
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In one paragraph

Article in Mycopathologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Júlia de Souza Silveira ValenteLaboratório de Micologia, Departamento de Microbiologia e Parasitologia, Prédio 18, Sala 14, Universidade Federal de Pelotas, Campus Capão do Leão, s/n°, Pelotas, RS, 96010-900, Brazil.
Anelise de Oliveira da Silva FonsecaLaboratório de Micologia, Departamento de Microbiologia e Parasitologia, Prédio 18, Sala 14, Universidade Federal de Pelotas, Campus Capão do Leão, s/n°, Pelotas, RS, 96010-900, Brazil.
Carolina Litchina BrasilLaboratório de Micologia, Departamento de Microbiologia e Parasitologia, Prédio 18, Sala 14, Universidade Federal de Pelotas, Campus Capão do Leão, s/n°, Pelotas, RS, 96010-900, Brazil.
Lauren SagaveCentro de Ciências Rurais, Universidade Federal de Santa Maria, Av. Roraima 1000, Prédio 44, Campus Universitário Camobi, Santa Maria, RS, 97105-900, Brazil.
Fernanda Cramer FloresCentro de Ciências da Saúde, Universidade Federal de Santa Maria, Av. Roraima 1000, Prédio 20, Campus Universitário Camobi, Santa Maria, RS, 97105-900, Brazil.
Cristiane de Bona da SilvaCentro de Ciências da Saúde, Universidade Federal de Santa Maria, Av. Roraima 1000, Prédio 20, Campus Universitário Camobi, Santa Maria, RS, 97105-900, Brazil.
Luís Antônio SangioniCentro de Ciências Rurais, Universidade Federal de Santa Maria, Av. Roraima 1000, Prédio 44, Campus Universitário Camobi, Santa Maria, RS, 97105-900, Brazil.
Luciana PötterCentro de Ciências Rurais, Universidade Federal de Santa Maria, Av. Roraima 1000, Prédio 44, Campus Universitário Camobi, Santa Maria, RS, 97105-900, Brazil.
Janio Morais SanturioCentro de Ciências da Saúde, Universidade Federal de Santa Maria, Av. Roraima 1000, Prédio 20, Campus Universitário Camobi, Santa Maria, RS, 97105-900, Brazil.
Sônia de Avila BottonCentro de Ciências Rurais, Universidade Federal de Santa Maria, Av. Roraima 1000, Prédio 44, Campus Universitário Camobi, Santa Maria, RS, 97105-900, Brazil.
Daniela Isabel Brayer PereiraLaboratório de Micologia, Departamento de Microbiologia e Parasitologia, Prédio 18, Sala 14, Universidade Federal de Pelotas, Campus Capão do Leão, s/n°, Pelotas, RS, 96010-900, Brazil. danielabrayer@gmail.com.ORCID http://orcid.org/0000-0003-4374-677X
Universidade Federal de Santa Maria · BRUniversidade Federal de Pelotas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pythium insidiosum is an important aquatic oomycete which can cause pythiosis in both animals and humans. This microorganism shows low susceptibility to antifungal drugs available. This study analyzed the in vitro antimicrobial activity of Melaleuca alternifolia in its free oil (FO) and nanoemulsion (NE) formulations against Brazilian P. insidiosum isolates. The antimicrobial activity evaluation was performed by the broth microdilution method according to CSLI M38-A2 document adapted to phytopharmaceuticals. Twenty-six P. insidiosum isolates were evaluated, and the minimum inhibitory concentration was determined at 100 % growth inhibition. Melaleuca alternifolia essential oil or FO was obtained commercially. The NE containing 1 % M. alternifolia essential oil was prepared by the spontaneous emulsification method. All P. insidiosum isolates evaluated showed minimum inhibitory concentrations (MIC) ranging from 531.5 to 2125 μg/mL for the FO formulation; MIC

Indexed as

Antifungal AgentsBrazilEmulsionsMelaleucaMicrobial Sensitivity TestsOils, VolatilePythiumAntifungal AgentsEmulsionsOils, VolatileMedicinal plantsNanostructured systemsOomycetePythiosis

Identifiers

PMID27544535
OpenAlexW2511910811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.