ArticlePsychoneuroendocrinology2016
Common variant in OXTR predicts growth in positive emotions from loving-kindness training.
Article in Psychoneuroendocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Interparental Positivity Spillover Theory: How Parents' Positive Relational Interactions Influence Children.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025Review
- Changes in peripheral oxytocin and vasopressin during a silent month-long Insight meditation retreat.Frontiers in endocrinology · 2024Article
- Symptom Science: Omics and Response to Non-Pharmacological Interventions.Biological research for nursing · 2021Article
- Does Meditation Training Influence Social Approach and Avoidance Goals? Evidence from a Randomized Intervention Study of Midlife Adults.Mindfulness · 2021Article
- The interaction between OXTR rs2268493 and perceived maternal care is associated with amygdala-dorsolateral prefrontal effective connectivity during explicit emotion processing.European archives of psychiatry and clinical neuroscience · 2020Article
- Decoding the biology of language and its implications in language acquisition.Journal of biosciences · 2019Review
- Subjective and Oxytocinergic Responses to Mindfulness Are Associated With Subjective and Oxytocinergic Responses to Sexual Arousal.Frontiers in psychology · 2019Article
- Genetics of language and its implications on language interventions.Journal of genetics · 2018Review
- A Systematic Review and Meta-analysis of the Effects of Meditation on Empathy, Compassion, and Prosocial Behaviors.Mindfulness · 2018Article
- Positive affective processes underlie positive health behaviour change.Psychology & health · 2018Article
- Additive Effects of 3,4-Methylenedioxymethamphetamine (MDMA) and Compassionate Imagery on Self-Compassion in Recreational Users of Ecstasy.Mindfulness · 2018Article
- Positive Emotion Correlates of Meditation Practice: A Comparison of Mindfulness Meditation and Loving-kindness Meditation.Mindfulness · 2017Article
- Influences of oxytocin and respiratory sinus arrhythmia on emotions and social behavior in daily life.Emotion (Washington, D.C.) · 2017Article
- Gaze-Following and Reaction to an Aversive Social Interaction Have Corresponding Associations with Variation in the OXTR Gene in Dogs but Not in Human Infants.Frontiers in psychology · 2017Article
- Understanding Engagement in and Affective Experiences During Physical Activity: The Role of Meditation Interventions.Psychosomatic medicineArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Ample research suggests that social connection reliably generates positive emotions. Oxytocin, a neuropeptide implicated in social cognition and behavior, is one biological mechanism that may influence an individual's capacity to extract positive emotions from social contexts. Because variation in certain genes may indicate underlying neurobiological differences, we tested whether several SNPs in two genes related to oxytocin signaling would show effects on positive emotions that were context-specific, depending on sociality. For six weeks, a sample of mid-life adults (N=122) participated in either socially-focused loving-kindness training or mindfulness training. During this timespan they reported their positive emotions daily. Five SNPs within OXTR and CD38 were assayed, and each was tested for its individual effect on daily emotions. The hypothesized three-way interaction between time, training type, and genetic variability emerged: Individuals homozygous for the G allele of OXTR rs1042778 experienced gains in daily positive emotions from loving-kindness training, whereas individuals with the T allele did not experience gains in positive emotions with either training. These findings are among the first to show how genetic differences in oxytocin signaling may influence an individual's capacity to experience positive emotions as a result of a socially-focused intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.