Evidence map›Paper›PMID 27543564›Full record

ArticleTobacco control2016

E-cigarette use is differentially related to smoking onset among lower risk adolescents.

Thomas A Wills, James D Sargent, Frederick X Gibbons, Ian Pagano, Rebecca Schweitzer

Open access · bronzeAbstract read
In one paragraph

Article in Tobacco control, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 6 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 6 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Article
  9. A Scoping Review of Vaping Among the Asian Adolescent Population.Asia-Pacific journal of public health · 2024
    Article
  10. Racial and Ethnic Disparities in Adolescent Combustible Tobacco Smoking From 2014 to 2020: Declines Are Lagging Among Non-Hispanic Black Youth.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
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  19. High School Seniors Who Used E-Cigarettes May Have Otherwise Been Cigarette Smokers: Evidence From Monitoring the Future (United States, 2009-2018).Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Thomas A WillsUniversity of Hawaii, Cancer Center, Honolulu, Hawaii, USA.
James D SargentGeisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
Frederick X GibbonsCenter for Health, Intervention & Prevention, University of Connecticut, Storrs, Connecticut, USA.
Ian PaganoUniversity of Hawaii, Cancer Center, Honolulu, Hawaii, USA.
Rebecca SchweitzerOffice of Public Health Studies, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Cancer Center of Hawaii · USDartmouth College · USUniversity of Connecticut · USUniversity of Hawaiʻi at Mānoa · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Xin Chen · 1996 to 2026
$56.2M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI HEDGES, JERRIS ROBERT, MOKUAU, NOREEN · 2012 to 2018
$21.1M
Self-Control as a Moderator for Effects of Mass Media on Adolescent Substance UseR01CA153154 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GIBBONS, FREDERICK X, WILLS, THOMAS A · 2010 to 2014
$2.9M
NCI NIH HHS P30 CA023108NCI NIH HHS P30 CA071789NCI NIH HHS R01 CA153154NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

objectiveE-cigarette use has been linked to onset of cigarette smoking among adolescents, but some commentators have suggested that this simply reflects high-risk adolescents being more likely to use e-cigarettes and to smoke. We tested whether the effect of e-cigarette use for smoking onset differs for youth who are lower versus higher on propensity to smoke.

methodsSchool-based survey with a longitudinal sample of 1136 students (9th-11th graders, mean age 14.7 years) in Hawaii, initially surveyed in 2013 (T1) and followed up 1 year later (T2). We assessed e-cigarette use, propensity to smoke based on 3 psychosocial factors known to predict smoking (rebelliousness, parental support and willingness to smoke), and cigarette smoking status. Analyses based on T1 never-smokers tested the relation of T1 e-cigarette use to T2 smoking status for participants lower versus higher on T1 propensity to smoke.

resultsThe relation between T1 e-cigarette use and T2 smoking onset was stronger among participants with lower levels of rebelliousness and willingness and higher levels of parental support. A multiple logistic regression analysis with T2 smoking as the criterion tested the cross-product of T1 e-cigarette use and T1 smoking propensity score; the interaction (OR=0.88, p=0.01) indicated a significantly larger effect for smoking onset among lower risk youth.

conclusionsThe results indicate e-cigarette use is a risk factor for smoking onset, not just a marker of high risk for smoking. This study provides evidence that e-cigarettes are recruiting lower risk adolescents to smoking, which has public health implications.

Indexed as

Adolescent BehaviorElectronic Nicotine Delivery SystemsSmokingAdolescentFemaleHumansMaleRiskSchoolsStudentsSurveys and QuestionnairesTobacco ProductsAddictionElectronic nicotine delivery devicesPriority/special populations

Identifiers

PMID27543564
PMCPMC5537057
OpenAlexW2517737540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.