Evidence map›Paper›PMID 27543490›Full record

ArticleWomen's health (London, England)2016

An update on the prevention of ovarian hyperstimulation syndrome.

Omar El Tokhy, Julia Kopeika, Tarek El-Toukhy

Open access · goldAbstract read
In one paragraph

Article in Women's health (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. The Trigger in IVF Cycles: Molecular Pathways and Clinical Implications.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Omar El TokhyFaculty of Medicine, Imperial College London, London, UK.
Julia KopeikaAssisted Conception Unit, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK.
Tarek El-ToukhyAssisted Conception Unit, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK tarek.el-toukhy@gstt.nhs.uk.
St Thomas' Hospital · GBImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian hyperstimulation syndrome is a potentially life-threatening, but preventable iatrogenic complication of in vitro fertilisation treatment. In recent years, new strategies have been developed to minimise the risk of ovarian hyperstimulation syndrome after in vitro fertilisation, including better at-risk patient identification prior to starting treatment, the use of a lower human chorionic gonadotrophin dose or alternative medication instead of human chorionic gonadotrophin to induce final oocyte maturation such as gonadotrophin-releasing hormone agonist and kisspeptin in antagonist cycles, cryopreservation of all embryos and delayed embryo transfer, and the use of oral dopamine agonists after oocyte retrieval. In this article, the advantages and limitations of those new developments are discussed and future directions towards establishment of an ovarian hyperstimulation syndrome-free in vitro fertilisation clinic are explored.

Indexed as

CabergolineChorionic GonadotropinDopamine AgonistsErgolinesEstradiolEstrogensFemaleFertility Agents, FemaleGonadotropin-Releasing HormoneHumansKisspeptinsLeuprolideLuteinizing HormoneOvarian Hyperstimulation SyndromeOvulation InductionRecombinant ProteinsCabergolineChorionic GonadotropinDopamine AgonistsErgolinesEstradiolEstrogensFertility Agents, FemaleGonadotropin-Releasing HormoneKISS1 protein, humanKisspeptinsLeuprolideLuteinizing HormoneRecombinant ProteinsReproductive Control Agentsdopamine agonistsgonadotrophin-releasing hormone agonistintra-cytoplasmic sperm injectionin vitro fertilisationkisspeptinluteal phaseoocyte retrievalovarian hyperstimulation syndromeprevention

Identifiers

PMID27543490
PMCPMC5373266
OpenAlexW2508731229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.