ArticleAfrican journal of primary health care & family medicine2016
Khat chewing and cirrhosis in Somaliland: Case series.
Article in African journal of primary health care & family medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Article
- Association Between Khat (Biomarker insights · 2026Article
- Article
- Hepatitis Associated withJournal of clinical medicine · 2025Article
- Chronic hepatitis B virus infection in Eastern Ethiopia: Clinical characteristics and determinants of cirrhosis.World journal of hepatology · 2024Article
- Review
- Risks of khat chewing on the cardiovascular, nervous, gastrointestinal, and genitourinary systems: A narrative review.Journal of family medicine and primary care · 2022Review
- Review
- Recent Advances in the Histopathology of Drug-Induced Liver Injury.Surgical pathology clinics · 2018Review
- Unexplained chronic liver disease in Ethiopia: a cross-sectional study.BMC gastroenterology · 2018Article
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Authors and funding
6 authors.
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Abstract
backgroundKhat chewing is common especially among men in East Africa and Yemen. It is generally viewed by the populace as a benign social custom. Several studies of ethnic Somali immigrants to Western countries suggest an association between khat chewing and hepatotoxicity, but the risk of hepatotoxicity related to khat chewing within African settings is not documented.
aimTo identify and describe liver disease without evidence of alcohol exposure or infectious etiology in khat chewers. SETTINGS: A university-affiliated teaching hospital in Somaliland.
methodsCases of cirrhosis of unknown cause were identified from the clinical practice of Al Hayatt Hospital in Borama, Somaliland, during 14 months beginning December 2012.
resultsEight Somali men aged 27-70 years living in Somaliland were identified with cirrhosis of otherwise unknown cause. All chewed khat habitually for many years (15-128 bundles per day times years of use). A liver biopsy of one man was consistent with khat hepatotoxicity. Four of the eight men died during the study period.
conclusionKhat chewing may be associated with health consequences including severe hepatotoxicity with cirrhosis.
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