Evidence map›Paper›PMID 27543091›Full record

ArticleThe Plant cell2016

Mitochondrial Defects Confer Tolerance against Cellulose Deficiency.

Zhubing Hu, Rudy Vanderhaeghen, Toon Cools, Yan Wang, Inge De Clercq, Olivier Leroux, Long Nguyen, Katharina Belt, A Harvey Millar, Dominique Audenaert and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
13.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
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  4. A fungal natural product that inhibits plant cellulose biosynthesis by disrupting cellulose synthase complexes.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  19. Allelochemicals ofPlant diversity · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Zhubing HuDepartment of Plant Systems Biology, VIB, B-9052 Gent, Belgium.
Rudy VanderhaeghenDepartment of Plant Systems Biology, VIB, B-9052 Gent, Belgium.
Toon CoolsDepartment of Plant Systems Biology, VIB, B-9052 Gent, Belgium.ORCID http://orcid.org/0000-0002-1258-5531
Yan WangDepartment of Botany, ARC Centre of Excellence in Plant Energy Biology, School of Life Science, La Trobe University, Bundoora 3086, Victoria, Australia.
Inge De ClercqDepartment of Plant Systems Biology, VIB, B-9052 Gent, Belgium.ORCID http://orcid.org/0000-0001-8125-1239
Olivier LerouxDepartment of Biology, Ghent University, B-9000 Gent, Belgium.
Long NguyenCompound Screening Facility, VIB, B-9052 Gent, Belgium.
Katharina BeltAustralian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley 6009, Australia.
A Harvey MillarAustralian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley 6009, Australia.
Dominique AudenaertCompound Screening Facility, VIB, B-9052 Gent, Belgium.
Pierre HilsonDepartment of Plant Systems Biology, VIB, B-9052 Gent, Belgium.ORCID http://orcid.org/0000-0003-4617-1908
Ian SmallAustralian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley 6009, Australia.ORCID http://orcid.org/0000-0001-5300-1216
Grégory MouilleInstitut Jean-Pierre Bourgin, INRA, Centre National pour la Recherche Scientifique, AgroParisTech, Université Paris-Saclay, 78026 Versailles Cedex, France.
Samantha VernhettesInstitut Jean-Pierre Bourgin, INRA, Centre National pour la Recherche Scientifique, AgroParisTech, Université Paris-Saclay, 78026 Versailles Cedex, France.
Frank Van BreusegemDepartment of Plant Systems Biology, VIB, B-9052 Gent, Belgium.ORCID http://orcid.org/0000-0002-3147-0860
James WhelanDepartment of Botany, ARC Centre of Excellence in Plant Energy Biology, School of Life Science, La Trobe University, Bundoora 3086, Victoria, Australia.ORCID http://orcid.org/0000-0001-5754-025X
Herman HöfteInstitut Jean-Pierre Bourgin, INRA, Centre National pour la Recherche Scientifique, AgroParisTech, Université Paris-Saclay, 78026 Versailles Cedex, France.
Lieven De VeylderDepartment of Plant Systems Biology, VIB, B-9052 Gent, Belgium lieven.deveylder@psb.vib-ugent.be.ORCID http://orcid.org/0000-0003-1150-4426
Ghent University · BEAgroParisTech · FRAustralian Research Council · AULa Trobe University · AUVIB-UGent Center for Plant Systems Biology · BENanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because the plant cell wall provides the first line of defense against biotic and abiotic assaults, its functional integrity needs to be maintained under stress conditions. Through a phenotype-based compound screening approach, we identified a novel cellulose synthase inhibitor, designated C17. C17 administration depletes cellulose synthase complexes from the plasma membrane in

Identifiers

PMID27543091
PMCPMC5059812
OpenAlexW2516057918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.