Trial reportAmerican journal of ophthalmology2016
Lid Wiper Microvascular Responses as an Indicator of Contact Lens Discomfort.
Trial report in American journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Presence of Eyelid Disease in Habitual Scleral Lens Wearers.Journal of clinical medicine · 2026Article
- The Association between Eye Sign and Capillaroscopy Changes in Patients with Scleroderma Spectrum Disease Presenting with Raynaud's Phenomenon, as Compared to the Normal Population.Medical journal of the Islamic Republic of Iran · 2026Article
- Vascular characteristics and haemodynamics of severe and mild pterygium: a quantitative analysis.Annals of medicine · 2025Observational
- Improved conjunctival microcirculation in diabetic retinopathy patients with MTHFR polymorphisms after Ocufolin™ Administration.Microvascular research · 2020Article
- A review of functional slit lamp biomicroscopy.Eye and vision (London, England) · 2019Review
- Quantitative analysis of conjunctival microvasculature imaged using optical coherence tomography angiography.Eye and vision (London, England) · 2019Article
- Inter-visit measurement variability of conjunctival vasculature and circulation in habitual contact lens wearers and non-lens wearers.Eye and vision (London, England) · 2019Article
- Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers.Investigative ophthalmology & visual science · 2018Article
- Contact lens wear and dry eyes: challenges and solutions.Clinical optometry · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeTo analyze quantitatively the alterations in the microvascular network of the upper tarsal conjunctiva, lid wiper, and bulbar conjunctiva relative to ocular discomfort after contact lens wear.
designA prospective, crossover clinical study.
methodsFunctional slit-lamp biomicroscopy was used to image the microvascular network of the upper tarsal conjunctiva, lid wiper, and bulbar conjunctiva. The microvascular network was automatically segmented, and fractal analyses were performed to yield the fractal dimension (D
resultsThere were no significant differences in D
conclusionsThis study is the first to show that the microvascular network of the lid wiper can be quantitatively analyzed in contact lens wearers. The microvascular responses of the lid wiper were significantly correlated with contact lens discomfort.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.