Evidence map›Paper›PMID 27542860›Full record

SynthesisUrology2016

A Systematic Review of Research Gaps in the Evaluation and Management of Localized Renal Masses.

Hiten D Patel, Emmanuel Iyoha, Phillip M Pierorazio, Stephen M Sozio, Michael H Johnson, Ritu Sharma, Eric B Bass, Mohamad E Allaf

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hiten D PatelJames Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD. Electronic address: hitenpatel@jhmi.edu.
Emmanuel IyohaJohns Hopkins Evidence-Based Practice Center, Johns Hopkins School of Public Health, Baltimore, MD.
Phillip M PierorazioJames Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD.
Stephen M SozioDepartment of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD.
Michael H JohnsonJames Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD.
Ritu SharmaJohns Hopkins Evidence-Based Practice Center, Johns Hopkins School of Public Health, Baltimore, MD.
Eric B BassJohns Hopkins Evidence-Based Practice Center, Johns Hopkins School of Public Health, Baltimore, MD.
Mohamad E AllafJames Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD.
Johns Hopkins University · US

Funding

Molecular Analysis and Precision Medicine in Renal Cell CarcinomaK01ES026838 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI JOHNSON, MICHAEL HIROSHI · 2015 to 2019
$821k
AHRQ HHS HHSA290201200007INIEHS NIH HHS K01 ES026838
6 · The paper itself

Abstract

The management of clinically localized renal masses suspicious for renal cell carcinoma varies, partially because of gaps in the evidence base. We conducted a systematic review to summarize research gaps for the evaluation of composite models for predicting malignancy; use of percutaneous renal sampling for diagnosis; and comparative effectiveness of surgery, thermal ablation, and active surveillance. A total of 147 studies, published in 150 articles, were identified. To promote improved patient care and health outcomes, we recommend incorporation of emerging biomarkers into validated composite models, standardization of biopsy protocols, standard reporting of clinical stage, and performance of prospective studies with objective selection criteria.

Indexed as

Disease ManagementKidney NeoplasmsQuality Indicators, Health CareBiomedical ResearchCombined Modality TherapyGlobal HealthHumansMorbiditySurvival RateUrology

Identifiers

PMID27542860
PMCPMC5598464
OpenAlexW2518480744

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.