Evidence map›Paper›PMID 27542854›Full record

ArticleEndocrine-related cancer2016

Genetic variants in thyroid cancer distant metastases.

Steven E Justiniano, Joseph P McElroy, Lianbo Yu, Ayse Selen Yilmaz, Kevin R Coombes, Leigha Senter, Rebecca Nagy, Paul Wakely, Stefano Volinia, Michelle Vinco and 4 more

Abstract readLetter
In one paragraph

Article in Endocrine-related cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Targeted sequencing of DNA/RNA combined with radiomics predicts lymph node metastasis of papillary thyroid carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  4. TheThyroid : official journal of the American Thyroid Association · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Steven E JustinianoDivision of EndocrinologyDiabetes, and Metabolism, The Ohio State University, Columbus, OH, USA.
Joseph P McElroyCenter for Biostatistics and Department of BioinformaticsThe Ohio State University, Columbus, OH, USA.
Lianbo YuCenter for Biostatistics and Department of BioinformaticsThe Ohio State University, Columbus, OH, USA.
Ayse Selen YilmazCenter for Biostatistics and Department of BioinformaticsThe Ohio State University, Columbus, OH, USA.
Kevin R CoombesCenter for Biostatistics and Department of BioinformaticsThe Ohio State University, Columbus, OH, USA.
Leigha SenterDivision of Human GeneticsThe Ohio State University, Columbus, OH, USA.
Rebecca NagyDivision of Human GeneticsThe Ohio State University, Columbus, OH, USA Guardant HealthInc, Redwood City, California, USA.
Paul WakelyDepartment of PathologyThe Ohio State University, Columbus, OH, USA.
Stefano VoliniaDepartment of MorphologySurgery and Experimental Medicine, University of Ferrara, Italy.
Michelle VincoDepartment of PathologyUniversity of Michigan, Ann Arbor, Michigan, USA.
Thomas J GiordanoDepartment of PathologyUniversity of Michigan, Ann Arbor, Michigan, USA Comprehensive Cancer CenterUniversity of Michigan, Ann Arbor, Michigan, USA.
Carlo M CroceDepartment of Molecular VirologyImmunology, and Genetics, The Ohio State University Wexner Medical Center and Arthur G. James Comprehensive Cancer Center, Columbus, Ohio, USA.
Motoyasu SajiDivision of EndocrinologyDiabetes, and Metabolism, The Ohio State University, Columbus, OH, USA.
Matthew D RingelDivision of EndocrinologyDiabetes, and Metabolism, The Ohio State University, Columbus, OH, USA Department of Molecular VirologyImmunology, and Genetics, The Ohio State University Wexner Medical Center and Arthur G. James Comprehensive Cancer Center, Columbus, Ohio, USA matthew.ringel@osumc.edu.

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Selective Modulation of Thyroidal RadioiodineP01CA124570 · NCI · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2008 to 2017
$23.4M
The Ohio State University and MD Anderson Cancer Center Thyroid Cancer SPOREP50CA168505 · NCI · OHIO STATE UNIVERSITY · PI KIRSCHNER, LAWRENCE S · 2013 to 2017
$10.9M
Cancer Gene Discovery to Identify Targetable TargetsR35CA197706 · NCI · OHIO STATE UNIVERSITY · PI CROCE, CARLO M · 2015 to 2021
$6.4M
NCI NIH HHS P01 CA124570NCI NIH HHS P30 CA016058NCI NIH HHS P50 CA168505NCI NIH HHS R35 CA197706
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Mutational AnalysisMutationAtaxia Telangiectasia Mutated ProteinsCase-Control StudiesCell Line, TumorFemaleGTP PhosphohydrolasesHumansINDEL MutationMaleMembrane ProteinsMutation, MissenseNeoplasm MetastasisPolymorphism, GeneticProto-Oncogene Proteins B-rafThyroid NeoplasmsAtaxia Telangiectasia Mutated ProteinsATM protein, humanBRAF protein, humanGTP PhosphohydrolasesMembrane ProteinsNRAS protein, humanProto-Oncogene Proteins B-raf

Identifiers

PMID27542854
PMCPMC5026957

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.