Evidence map›Paper›PMID 27541736›Full record

ArticleInternational journal of cancer2016

Aluminium chloride promotes tumorigenesis and metastasis in normal murine mammary gland epithelial cells.

Stefano J Mandriota, Mirna Tenan, Paolo Ferrari, André-Pascal Sappino

Open access · hybridAbstract read
In one paragraph

Article in International journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
7.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The MAK collection for occupational health and safety · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?International journal of environmental research and public health · 2022
    Review
  9. Article
  10. Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis.International journal of molecular sciences · 2020
    Article
  11. The Health Effects of Aluminum Exposure.Deutsches Arzteblatt international · 2017
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Stefano J MandriotaCenter of Oncology, Faculty of Medicine, University of Geneva, Switzerland. stefano.mandriota@fondation.grangettes.ch.ORCID http://orcid.org/0000-0001-6071-4804
Mirna TenanLaboratoire de cancérogenèse environnementale, Fondation des Grangettes, Chêne-Bougeries, Switzerland.
Paolo FerrariLaboratoire de cancérogenèse environnementale, Fondation des Grangettes, Chêne-Bougeries, Switzerland.
André-Pascal SappinoCenter of Oncology, Faculty of Medicine, University of Geneva, Switzerland.
Hirslanden Clinique des Grangettes · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aluminium salts, present in many industrial products of frequent use like antiperspirants, anti-acid drugs, food additives and vaccines, have been incriminated in contributing to the rise in breast cancer incidence in Western societies. However, current experimental evidence supporting this hypothesis is limited. For example, no experimental evidence that aluminium promotes tumorigenesis in cultured mammary epithelial cells exists. We report here that long-term exposure to concentrations of aluminium-in the form of aluminium chloride (AlCl

Indexed as

Aluminum ChlorideAluminum CompoundsAnimalsCell LineCell Transformation, NeoplasticChloridesDisease Models, AnimalEpithelial CellsFemaleLung NeoplasmsMammary Neoplasms, ExperimentalMiceNeoplasm MetastasisXenograft Model Antitumor AssaysAluminum ChlorideAluminum CompoundsChloridesaluminiumantiperspirantsbreast cancercarcinogenmetastasismouse models of cancer

Identifiers

PMID27541736
PMCPMC5095782
OpenAlexW2513045322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.