ArticleEnvironmental science and pollution research international2016
Metal toxicokinetics and metal-driven damage to the gut of the ground beetle Pterostichus oblongopunctatus.
Article in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 citing papers in PubMed, 28 citations in OpenAlex.
- Rebuttal to Correspondence on "Mortality Pattern ofEnvironmental science & technology · 2024Article
- Transfer of elements from soil to earthworms and ground beetles in boreal forest.Radiation and environmental biophysics · 2023Article
- Autophagy: a necessary defense against extreme cadmium intoxication in a multigenerational 2D experiment.Scientific reports · 2020Article
- Article
- Pollution intensity-dependent metal accumulation in ground beetles: a meta-analysis.Environmental science and pollution research international · 2019Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toxicokinetics makes up the background for predicting concentrations of chemicals in organisms and, thus, ecological risk assessment. However, physiological and toxicological mechanisms behind toxicokinetics of particular chemicals are purely understood. The commonly used one-compartment model has been challenged recently, showing that in the case of metals it does not describe the pattern observed in terrestrial invertebrates exposed to highly contaminated food. We hypothesised that the main mechanism shaping toxicokinetics of metals in invertebrates at high exposure concentrations in food is the cellular damage to the gut epithelial cells. Gut damage should result in decreased metal assimilation rate, while shedding the dead cells - in increased elimination rate. We performed a typical toxicokinetic experiment, feeding the ground beetles Pterostichus oblongopunctatus food contaminated with Cd, Ni or Zn at 40 mM kg
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