Evidence map›Paper›PMID 27540582›Full record

ArticleEndoscopy international open2016

Transpapillary biliary stenting is a risk factor for pancreatic stones in patients with autoimmune pancreatitis.

Hiroyuki Matsubayashi, Yoshihiro Kishida, Tomohiro Iwai, Katsuyuki Murai, Masao Yoshida, Kenichiro Imai, Yusuke Yamamoto, Masataka Kikuyama, Hiroyuki Ono

Open access · goldAbstract read
In one paragraph

Article in Endoscopy international open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Management of IgG4-Related Disease.Current rheumatology reports · 2026
    Review
  3. Steroid Therapy and Steroid Response in Autoimmune Pancreatitis.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hiroyuki MatsubayashiDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Yoshihiro KishidaDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Tomohiro IwaiDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Katsuyuki MuraiDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Masao YoshidaDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Kenichiro ImaiDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Yusuke YamamotoDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Masataka KikuyamaDivision of Gastroenterology, Shizuoka General Hospital, Shizuoka, Japan.
Hiroyuki OnoDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Shizuoka Cancer Center · JPShizuoka General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND STUDY

aimPancreatic stones occasionally develop in autoimmune pancreatitis (AIP), often worsen endocrine and exocrine functions, and occasionally cause pain attacks. However, the risks of pancreatic stones in AIP have been poorly studied. The aim of this study was to analyze the risk factors associated with pancreatic stone formation in cases of AIP. PATIENTS AND

methodsIn total, 50 patients with AIP (39 males, 11 females; mean age 64.0 years), followed up for at least a year, were analyzed for their demographic and clinical findings and pancreatic stone occurrence.

resultsIn total, 50 patients were followed up for an average of 59.7 (12 - 120) months, with steroid treatment in 44 patients (88 %); pancreatic stones occurred in 14 (28 %) patients after the diagnosis of AIP and endoscopic treatment was needed in one patient with pain attack. The pancreatic stones appeared only in patients with long follow-up period (P < 0.001, 83.9 months vs. 49.6 months), biliary stenting (odds ratio [OR]: 8.40, P = 0.010), relapse (OR: 6.20, P = 0.023), jaundice (OR: 5.40, P = 0.019), and swelling of the duodenal major papilla (OR: 4.67, P = 0.040). Biliary stenting was placed for an average of 9.9 months in 27 patients. Multivariate analysis revealed a significant association only with biliary stenting (P = 0.011). The stones appeared relatively earlier in patients with stones in the main pancreatic duct or Santorini duct (22.1 months) than in patients where pancreatic stones developed elsewhere (53.4 months) (P = 0.018).

conclusionsThe risk of pancreatic stone development should be taken into account when a biliary stent is placed in patients with AIP.

Identifiers

PMID27540582
PMCPMC4988851
OpenAlexW2511828274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.