Evidence map›Paper›PMID 27540270›Full record

ArticleBioinformatics (Oxford, England)2016

A new correlation clustering method for cancer mutation analysis.

Jack P Hou, Amin Emad, Gregory J Puleo, Jian Ma, Olgica Milenkovic

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. An Effective Graph Clustering Method to Identify Cancer Driver Modules.Frontiers in bioengineering and biotechnology · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jack P HouDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Amin EmadDepartment of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Gregory J PuleoDepartment of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Jian MaDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Olgica MilenkovicDepartment of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Funding

Mapping Technology DevelopmentU54DK107965 · NIDDK · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BELMONT, ANDREW STEVEN · 2015 to 2019
$8.6M
Genomic Compression: From Information Theory to Parallel AlgorithmsU01CA198943 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MILENKOVIC, OLGICA, WEISSMAN, TSACHY · 2015 to 2017
$1.4M
Scalable Cancer Genomics via Nanocoding and SequencingR33CA182360 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MA, JIAN, SCHWARTZ, DAVID C. · 2015 to 2017
$1.1M
NCI NIH HHS R33 CA182360NCI NIH HHS U01 CA198943NIDDK NIH HHS U54 DK107965
6 · The paper itself

Abstract

motivationCancer genomes exhibit a large number of different alterations that affect many genes in a diverse manner. An improved understanding of the generative mechanisms behind the mutation rules and their influence on gene community behavior is of great importance for the study of cancer.

resultsTo expand our capability to analyze combinatorial patterns of cancer alterations, we developed a rigorous methodology for cancer mutation pattern discovery based on a new, constrained form of correlation clustering. Our new algorithm, named C AVAILABILITY AND IMPLEMENTATION: The source code for the C

Indexed as

AlgorithmsCluster AnalysisBreast NeoplasmsComputational BiologyDNA Mutational AnalysisFemaleGene Regulatory NetworksGlioblastomaHumansMutation

Identifiers

PMID27540270
PMCPMC6078169

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.